Results 11 to 20 of about 4,590 (177)
Development of tetraploidy in salmonids
Genetics Selection Evolution, 1980 Refstie T
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The consequences of tetraploidy and aneuploidy [PDF]
Journal of Cell Science, 2008 Polyploidy, an increased number of chromosome sets, is a surprisingly common phenomenon in nature, particularly in plants and fungi. In humans, polyploidy often occurs in specific tissues as part of terminal differentiation. Changes in ploidy can also result from pathophysiological events that are caused by viral-induced cell fusion or erroneous cell ...
Storchova, Z., Kuffer, C.
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Discovery of tetraploidy in a mammal [PDF]
Nature, 1999 The red viscacha rat is unaffected by having double the usual number of chromosomes. Polyploidy, or having more than a pair of each type of chromosome, is considered to be unlikely in mammals because it would disrupt the mechanism of dosage compensation that normally inactivates one X chromosome in females1.
M H, Gallardo +4 more
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Tetraploidy in hydatidiform moles [PDF]
Human Reproduction, 2013 How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins?Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from a tetraploid zygote.
Sundvall Germeys, Linda Karin M +5 more
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Clinicopathological analysis of near-tetraploidy/tetraploidy acute myeloid leukaemia [PDF]
Journal of Clinical Pathology, 2015 Aims Near-tetraploidy/tetraploidy (NT/T) is a rare cytogenetic alteration in acute myeloid leukaemia (AML). NT/T-AML is categorised as complex cytogenetics and therefore, presumed to have an unfavourable prognosis.
Changlee S, Pang +2 more
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The frequency and importance of polyploidy in tropical rainforest tree radiations. [PDF]
New PhytolSummary The presence of more than two copies of the genome in an organism, termed ‘polyploidy’, is a crucial force in plant evolution, generating genetic, phenotypic and ecological diversity. [Correction added on 22 January 2026, after first online publication: the preceding sentence has been corrected.] The Amazonian tree flora is the most species ...
Schley RJ +9 more
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Induction to tetraploidy in Pacific oysters (Crassostrea gigas)
Acta Scientiarum: Animal Sciences, 2022 As an alternative to the use of cytochalasin B (CB), 6-dimethylamino-purine (6-DMAP) and thermal shock (heat shock by increasing the temperature from 25 to 36ºC) could be used to induce tetraploidy in Pacific oyster (Crassostrea gigas) diploids ...
Emílio Mateus Costa Melo +3 more
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Tetraploidy and tumor development
Oncotarget, 2014 Tetraploid cells, which contain a doubled chromosomal content, are known to facilitate tumorigenesis [1]. Two specific characteristics of tetraploid cells play major roles in promoting neoplastic transformation. First, proliferating tetraploid cells are genomically unstable and accumulate both numerical and structural chromosomal abnormalities.
Sanghee, Lim, Neil J, Ganem
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Tetraploidy causes chromosomal instability in acentriolar mouse embryos
Nature Communications, 2019 During cell division, tetraploidy can drive chromosomal instability (CIN) via supernumerary centrosomes, but it is unclear if this is the only route to CIN. Here the authors show that, in early mouse embryos, tetraploidy can drive chromosomal instability
Lia Mara Gomes Paim, Greg FitzHarris
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The fate of extra centrosomes in newly formed tetraploid cells: should I stay, or should I go?
Frontiers in Cell and Developmental Biology, 2023 An increase in centrosome number is commonly observed in cancer cells, but the role centrosome amplification plays along with how and when it occurs during cancer development is unclear. One mechanism for generating cancer cells with extra centrosomes is
Mathew Bloomfield, Daniela Cimini
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