Results 111 to 120 of about 5,897 (227)

Synthesis of 5-substituted tetrazoles - a comparison of classical synthetic aproach with synthesis under microvawe activation

, 2009
1. Abstract Chemistry of 5-substituted tetrazoles has been the subject of intense investigation during last ten years. 5-substituted tetrazoles have found widespread use in many branches of industry, especially in pharmacy.
Gela, Petr
core  

Direct C−H Arylation and Alkenylation of 1-Substituted Tetrazoles: Phosphine As Stabilizing Factor

, 2016
Direct arylation and alkenylation of 1-substituted tetrazoles was achieved via Pd catalysis in the presence of CuI and Cs2CO3. Unlike the related reactions of imidazoles and purines, phosphine ligand was necessary to prevent the intermediate tetrazolyl ...
Richard Lubojacký (2328724), Marcel Špulák (2328727), Jiří Kuneš (1233537), Milan Pour (1676887), Petr Šenel (2328721)   +4 more
core   +1 more source

Design and Synthesis of Laser-Activatable Tetrazoles for a Fast and Fluorogenic Red-Emitting 1,3-Dipolar Cycloaddition Reaction

, 2016
The design and synthesis of a new class of laser light activatable tetrazoles with extended π-systems is reported. Upon 405 nm laser light irradiation, these bithiophene-substituted tetrazoles underwent extremely fast 1,3-dipolar cycloaddition reactions ...
Zhipeng Yu (1311822), Peng An (158722), Qing Lin (5273)   +2 more
core   +1 more source

1-Alkyl-5-((di)alkylamino) Tetrazoles: Building Blocks for Peptide Surrogates

, 2016
An approach to the synthesis of 1-alkyl-5-((di)­alkylamino)­tetrazoles by nucleophilic substitution in 1-alkyl-5-sulfonyltetrazoles with anions generated from the primary or secondary amines was developed.
Igor V. Komarov (579414), Dmitriy M. Volochnyuk (1617088), Andriy V. Tymtsunik (2121727), Vitaliy A. Bilenko (2121724), Serhiy O. Kokhan (2121730), Oleksandr O. Grygorenko (1617082)   +5 more
core   +1 more source

Síntesis de tetrazoles a partir de aldononitrilos acetilados [PDF]

, 1974
El presente trabajo tuvo por objeto la síntesis de 5—(poliacetoxialquil)-tetrazoles a partir de algunos aldononitrilosacetilados. A partir de los 5-(poliacetoxialquil)-tetrazolesse obtuvieron los 5-(polihidroxialquil)-tetrazoles correspondientes.
Seldes, Alicia Marta
core   +1 more source

Synthesis and Anti-inflammatory Activity of some Substituted Tetrazoles

, 1991
Department of Chemistry, University of Jammu, Jammu-180 001 Manuscript received 1 August 1990, revised 17 January 1991, accepted 23 April 1991 Synthesis and Anti-inflammatory Activity of some Substituted ...
VERSHA WAZIR, G. B. SINGH, SURJIT SINGH, P. L. KACHROO, RAJIVE GUPTA   +4 more
core   +1 more source

Regioselective N-2 Alkylation of Tetrazoles with Phenacyl Halides under Mechanochemical Conditions and Its Application to a Solid-State Synthesis of the Antiepileptic Drug Cenobamate

Tetrazole derivatives are very important compounds in medicinal chemistry, and their preparation typically requires multistep sequences. Therefore, the regioselective N-alkylation of tetrazoles is a highly significant synthetic objective.
Gómez-Carpintero Jiménez, Jorge, Menéndez Ramos, José Carlos, Mazzetta, Anna Maria, Bepirszcz, Kamila, Sánchez Cebrián, Juan Domingo, González Matilla, Juan Francisco   +5 more
core   +1 more source

Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process

, 2017
A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions.
Laurent, El Kaim, Cárdenas-Galindo, Luis Edilberto, Islas-Jácome, Alejandro, Cortes-García, Carlos Jesús, Gámez-Montaño, Rocío   +4 more
core  

1,5-Disubstituted Tetrazoles as Promising Anticancer Resistance Agents: A Chemoinformatic Characterization. [PDF]

ACS Omega
Garibay-Manríquez C, Díaz-Cervantes E, Chacón-García L, Martinez-Mayorga K, Cortés-García CJ.   +4 more
europepmc   +1 more source

Exploring Biofilm Inhibition Potential of Imidazo-Pyridine Linked Tetrazoles Against Candida albicans: Synthesis, Biological Evaluation With Computational Studies. [PDF]

Chem Biol Drug Des
Madalambika, Kumar AC, BharathKumar PM, Gowda KBV, Ramu R, Naik N.   +5 more
europepmc   +1 more source