Results 101 to 110 of about 5,897 (227)

X-ray, IR, NMR, UV-visible spectra and DFT analysis of 5-aryloxy-(1H)-tetrazoles, structure, conformation and tautomerism

, 2014
The predominant tautomeric forms of N1–H, N2–H of 5-(2,6-dimethyl- and 5-(2,6-diisopropylphenoxy)-(1H)-tetrazoles were analyzed at B3LYP method using 6-311G(d,p) basis set in the gas phase.
Pesyan, Nader Noroozi, Mohamed Tahir, Mohamed Ibrahim, Bavafa, Sadeghali, Soleimannejad, Jannet, Enayati, Mohammad Samim, Dadrass, Alireza, Ostadhosseini, Narges, Sahin, Ertan, Hoseinpour, Sajedin   +8 more
core   +1 more source

An Efficient One-Pot Three-Component Synthesis of Novel Sulfanyl Tetrazoles Using Ionic Liquids

Journal of Chemistry, 2013
An efficient, simple, and environmentally benign method for the synthesis of novel sulfanyl tetrazoles has been achieved by one-pot three-component reaction of phenacyl bromides/3-(2-bromoacetyl)coumarins with KSCN and NaN3 using [Bmim]BF4 ionic liquid ...
Sankari Kanakaraju, Bethanamudi Prasanna, G. V. P. Chandramouli   +2 more
doaj   +1 more source

TETRAZOLES OF MANNO-PYRANOSES AND RHAMNO-PYRANOSES - INHIBITION OF GLYCOSIDASES BY TETRAZOLES AND OTHER MANNOSE MIMICS

, 1995
The synthesis of tetrazoles derived from D-mannopyranose and D-rhamnopyranose from L-gulonolactone is described. These and other materials are assessed as inhibitors of human liver glycosidases and delineate some structural features required for α- and β-
HYETT, D, SMITH, C, FLEET, G, WINCHESTER, B, DAVIS, B, HACKETT, L, BRANDSTETTER, T   +6 more
core   +1 more source

TETRAZOLES: SYNTHESIS, MEDICINAL, AND MULTIFUNCTIONAL SIGNIFICANCE

Tetrazoles are nitrogen-rich five-membered heterocyclic compounds that have emerged as highly significant structural motifs in modern synthetic, medicinal, and materials chemistry.
Dr. Amarender K, Dr. Nalaparaju Nagaraju, Dr. Yelchuri Padmaja, Dr. B. Vijaya Lakshmi   +3 more
core   +1 more source

Structural and Functional Insights Into (S)‐5′‐C‐Guanidinopropyl Uridine‐Modified Oligonucleotides With 2′‐O‐Methyl and 2′‐Fluoro Substitutions for RNAi Therapeutics

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Novel (S)‐5′‐guanidinopropyl uridine analogs bearing 2′‐O‐methyl or 2′‐fluoro substitutions enhance nuclease resistance and mismatch discrimination while preserving A‐form RNA structure and potent RNAi activity. These modifications provide a promising strategy for improving the stability, specificity, and therapeutic potential of siRNA‐based medicines.
Sugahara Masaki, Elsayed M. Mahmoud, Shuichi Sakamoto, Yoshihito Ueno   +3 more
wiley   +1 more source

Proximity-assisted cycloaddition reactions of ω-azido cyanohydrin ethers: Synthesis of diversely functionalized bicyclic tetrazoles

, 2010
Aliphatic azidonitriles separated by three or four carbon atoms undergo facile cyclo-additions in the presence of BF3·OEt2 at room temperature or lower, to give bicyclic tetrazoles.
Stephen Hanessian, Caroline Chenel, Edgar Haak, Daniel Simard, Vlad Bulat, Benoît Deschênes-Simard   +5 more
core   +1 more source

Supramolecular cyclodextrin catalysis for green click synthesis of tetrazoles

Results in Chemistry
Tetrazole-containing molecules have attracted considerable interest owing to their chemical stability and wide-ranging biological applications. In this study, cyclodextrins (CDs) were investigated as phase-transfer catalysts for the green synthesis of 5 ...
Riham Sghyar, Mouad Lahyaoui, Amine Ez-zoubi, Zainab Jabri, Ahmed Mazzah, Amal Haoudi, Noura Aflak, Salah Eddine Sbiaa, Oussama Moussaoui, Youssef Kandri Rodi   +9 more
doaj   +1 more source

Solid-Phase Synthesis of 5-Biphenyl-2-yl-1H-tetrazoles

, 2016
The combinatorial synthesis of novel biphenyl tetrazoles is described. Key steps include the simultaneous biphenyl formation and phenol deallylation under Suzuki cross-coupling conditions as well as the tetrazole ring formation on solid support.
Frank Hülshorst (2721163), Nils Griebenow (2583676), Olga Kivrakidou (2721166), Stefan Bräse (2454700)   +3 more
core   +1 more source

Tetrazoles of manno- and rhamno-furanoses

, 1999
The synthesis of tetrazoles derived from D-mannofuranose and both enantiomers of rhamnofuranose provides the first examples of tetrazole analogues of carbohydrates in the furanose form.
Fleet, George, Smith, C, Fleet, GWJ, Nash, RJ, Watson, AA, Davis, BG, Davis, Benjamin   +6 more
core   +1 more source

ZNCL2/ALCL3/SILICA (ZAS) AS AN EFFECTIVE HETEROGENEOUS CATALYST FOR THE SYNTHESIS OF 5-RYLOXYTETRAZOLES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2012
A simple and efficient method for preparation of 5-aryloxy tetrazoles (3a-h) from arylcyanates (1a-h) with using ZnCl2/AlCl3/silica (ZAS) as an effective heterogeneous catalyst in solvent free are described with excellent yields and high purity. The rate
F. Khamooshi, B. H. K. Jhaleh
doaj