Results 91 to 100 of about 18,306 (270)
Concise Synthesis of Tetrazole Macrocycle [PDF]
Organic Letters, 2017 A concise two step synthesis of tetrazole containing macrocycles from readily accessible starting materials is presented. The first step comprises a chemoselective amidation of amino acid derived isocyanocarboxylicacid esters with unprotected symmetrical diamines to afford diverse α-isocyano-ω-amines. In the second step, the α-isocyano-ω-amines undergo
Abdelraheem +7 more
openaire +4 more sources
ChemistryEurope, Volume 4, Issue 4, April 2026.We report a biosynthesis‐inspired ring distortion approach that involves oxidative ring cleavage, ring rearrangement, and ring expansion reactions from a diverse collection of indole alkaloids and derivatives. This chemical synthesis approach led to the synthesis of >25 distinct chemotypes from 14 indole alkaloids.
Derek A. Leas +7 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 4, April 2026.The pictorial illustration of the applications of polymers of intrinsic microporosity extraordinary porous organic polymers with high surface areas, pore radii, pore volumes, high permeability, high diffusivity, high selectivity, and high thermal stability, as suitable filters or purifiers for water contaminated with pharmaceutical and organic dyes ...
Martins O. Omorogie
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2017 Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis. The combination of IMCRs in a consecutive or sequential fashion further extends the complexity of the molecules obtained.
Angélica de Fátima S. Barreto +2 more
doaj +1 more source
Nitrile ylides: allenic and propargylic structures from pyrazinylnitrenes. Experimental and theoretical characterization [PDF]
, 2014 Matrix photolysis of 2-pyrazinyl azides/tetrazolo[1,5-a]pyrazines generates nitrile ylides 15 via pyrazinylnitrenes 13 and triazacycloheptatetraenes 14.
Addicott, Chris +6 more
core +3 more sources
Advanced Synthesis and Catalysis, 2018 . The preparation of 5-substituted 1H-tetrazoles was efficiently achieved by reaction of trimethylsilylazide with nitriles using a triorganotin alkoxide precatalyst. The reaction mechanism was first investigated using a homogeneous tributyltin derivative
Jean-Mathieu Chrétien +6 more
semanticscholar +1 more source
British Journal of Haematology, Volume 208, Issue 4, Page 1437-1442, April 2026.We show how the loss of activity of the translation initiation factor EIF5A2—either through gene hypermethylation or pharmacologic inhibition of its highly specific hypusine post‐translational modification—induces venetoclax sensitivity in acute myeloid leukaemia (AML) cells.
Eva Crespo‐García +5 more
wiley +1 more source
Investigation of structural effects on the reactivity of heterocyclic bioactive compounds [PDF]
, 2008 Tese de dout., Química, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2008In the course of this investigation, structural effects on the reactivity of a series of heterocyclic compounds, in particular tetrazole and benzisothiazole ...
Frija, L.
core
Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries [PDF]
, 2010 Blood flow reduction induces inward remodeling of resistance arteries (RAs). This remodeling occurs in ischemic diseases, diabetes and hypertension. Nonetheless, the effect of flow reduction per se, independent of the effect of pressure or metabolic ...
A.L. Guihot +9 more
core +3 more sources
Compound Library Screening Identified Cladribine as a Novel Radiosensitizer for Prostate Cancer
Cancer Science, Volume 117, Issue 4, Page 1136-1147, April 2026.The combination of cladribine and irradiation significantly suppressed the growth of DU145‐derived tumors compared with the DMSO plus irradiation group in the mouse model. In addition, it also elevated the percentage of γH2AX‐positive cells after irradiation.
Toshiki Oka +26 more
wiley +1 more source