Results 71 to 80 of about 6,074 (218)
Brønsted acid-catalyzed alkylation of tetrazoles with alcohols [PDF]
Tetrazoles hold significant pharmaceutical importance, being a key component in various drugs with hypertensive, antimicrobial, antiviral, antiallergic, cytostatic and nootropic biological activities.
Butt, Arsala
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CHIMIA, 1975 Sodium azide or trimethylsilylazide react with N,N-dimethylphosgenimonium chloride by monosubstitution yielding N,N-dimethyl-azidochloromethylen-imonium chloride which can be isolated.
H.G. Viehe, P. George
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Designing the First Hydroxylamine Substituted Tetrazole With N,O‐Dimethylhydroxylamine
Zeitschrift für anorganische und allgemeine Chemie, EarlyView.Despite decades of tetrazole chemistry, hydroxylamine‐substituted variants have remained unknown. This work reports the first synthesis of a 5‐hydroxylamine substituted tetrazole via cyanogen azide and N,O‐dimethylhydroxylamine, yielding the free‐base compound and its hydrochloride salt.
Jake E. Zuckerman +3 more
wiley +1 more source
Structural and biochemical basis for retinol‐binding protein 4 antagonism by tinlarebant
British Journal of Pharmacology, EarlyView.Background and Purpose Retinol‐binding protein 4 (RBP4) is a member of the lipocalin superfamily that is connected to disease states such as insulin resistance, fatty liver disease and ocular disorders including Stargardt disease. Several retinoid and non‐retinoid antagonists of this protein have been developed for potential clinical use, but none have
Marco Bassetto, Philip D. Kiser
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, 2014 The predominant tautomeric forms of N1–H, N2–H of 5-(2,6-dimethyl- and 5-(2,6-diisopropylphenoxy)-(1H)-tetrazoles were analyzed at B3LYP method using 6-311G(d,p) basis set in the gas phase.
Pesyan, Nader Noroozi +8 more
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Beilstein Journal of Organic Chemistry, 2017 Isocyanide-based multicomponent reactions (IMCRs) allow the construction of relatively complex molecules through a one-pot synthesis. The combination of IMCRs in a consecutive or sequential fashion further extends the complexity of the molecules obtained.
Angélica de Fátima S. Barreto +2 more
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Aggregate, Volume 7, Issue 11, November 2026.A node‐encoding strategy programs lanthanide ions into water‐stable polyhedra with predictable architectures, integrating luminescence and magnetic resonance contrast for optical and magnetic resonance bioimaging. ABSTRACT Multinuclear lanthanide‐organic polyhedra offer attractive molecular scaffolds for biomedical imaging, while their predictable ...
Xin‐Ran Gan +9 more
wiley +1 more source
Journal of Heterocyclic Chemistry, Volume 63, Issue 11, Page 1637-1643, November 2026.One‐pot gold(I)‐catalysts synthesis was developed in order to prepare N‐alkenyl 2‐pyridonyl azides. This method provides a series of N‐alkenyl 2‐pyridonyl azides in moderate to excellent yields (up to 94%). ABSTRACT A novel strategy, involving the preparation of gold‐catalyzed cyclization salts and the rearrangement of these salts in the presence of ...
Ali Osman Karatavuk
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New advances in chemistry of tetrazoles
, 2014 В обзоре обобщены результаты исследований, проведенных в НИИ ФХП БГУ в области химии производных тетразола за последнее пятилетие. Основное внимание уделено наиболее значимым направлениям в синтезе тетразолов: – гетероциклизации первичных аминов с ...
Войтехович, Сергей Владимирович +3 more
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In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi
Molecules, 2015 In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus)
Pedro A. Cano +8 more
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