Results 51 to 60 of about 6,074 (218)

Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis

open access: yesMolecules, 2010
Tetrazoles remain a challenge to photochemists. Photolysis leads to cleavage of the tetrazolyl ring, may involve various photodegradation pathways and may produce a diversity of photoproducts, depending on the structure and conformational flexibility of ...
Luís Miguel Teodoro Frija   +2 more
doaj   +1 more source

Synthesis and In Vitro Antiproliferative Activity of Novel Androst-5-ene Triazolyl and Tetrazolyl Derivatives

open access: yesMolecules, 2011
A straightforward and reliable method for the regioselective synthesis of steroidal 1,4-disubstituted triazoles and 1,5-disubstituted tetrazoles via copper(I)-catalyzed cycloadditions is reported. Heterocycle moieties were efficiently introduced onto the
János Wölfling   +7 more
doaj   +1 more source

Rapid microwave promoted heterocyclization of primary amines with triethyl orthoformate and sodium azide using zinc sulfide nanoparticles as recyclable catalyst

open access: yesGreen Chemistry Letters and Reviews, 2018
Microwave assisted synthesis of 1-substituted-1H-tetrazoles was developed using zinc sulfide nanoparticles as heterogeneous catalyst under solvent free conditions.
Hossein Naeimi   +2 more
doaj   +1 more source

Synthesis of 1,5 and 2,5-disubstituted tetrazoles using NiO nanoparticles and their evaluation as antimicrobial agents [PDF]

open access: yesNanomedicine Research Journal, 2019
Treatments of tetrazolate salts prepared in situ from various aldehyde; malononitrile and sodium azide in the presence of NiO nanoparticles with benzyl bromide gave the corresponding 1,5- and 2,‌5-disubstituted tetrazoles.
Javad Safaei-Ghomi   +3 more
doaj   +1 more source

Mechanistic Understanding and Reactivity Analyses for the Photochemistry of Disubstituted Tetrazoles

open access: yes, 2023
The photolysis of tetrazoles has undergone extensive research. However, there are still some problems to be solved in terms of mechanistic understanding and reactivity analyses, which leaves room for theoretical calculations.
Yanting Yang (4786464)   +17 more
core   +1 more source

Diazocarbonyl and Related Compounds in the Synthesis of Azoles

open access: yesMolecules, 2021
Diazocarbonyl compounds have found numerous applications in many areas of chemistry. Among the most developed fields of diazo chemistry is the preparation of azoles from diazo compounds.
Anton Budeev   +3 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

A Crystallographic Study of a Novel Tetrazolyl-Substituted Nitronyl Nitroxide Radical

open access: yesCrystals, 2018
Spin-labelled compounds are widely used in chemistry, physics, biology, and material sciences, but the directed synthesis of some functionalized organic radicals is still a challenge.
Vasily E. Romanov   +6 more
doaj   +1 more source

Facile synthesis of tetrazoles catalyzed by the new copper nano-catalyst

open access: yesGreen Chemistry Letters and Reviews, 2020
Despite various methods for preparation of tetrazoles, they are suffering from some disadvantages such as low yield, long reaction times and harsh reaction conditions, and there are still high demands to improve the common procedures to solve problems ...
Vahideh Khorramabadi   +2 more
doaj   +1 more source

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah   +8 more
wiley   +1 more source

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