Results 31 to 40 of about 5,897 (227)

Crystal structure of poly[di-μ-aqua-{5-[(1Z)-2-(4-chlorophenyl)-1-cyanoethenyl]-1,2,3,4-tetrazol-1-ido-κN1}sodium]

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Na(C10H5ClN5)(H2O)2]n, infinite chains of [Na(H2O)2]+ cations having a diamond-shaped cross-section and running parallel to the b axis are formed.
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Ahmed M. M. El-Saghier, Mustafa R. Albayati   +4 more
doaj   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

Angewandte Chemie, EarlyView.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang, Hsuan‐Hung Liao   +1 more
wiley   +2 more sources

Concise Synthesis of Tetrazole Macrocycle [PDF]

Organic Letters, 2017
A concise two step synthesis of tetrazole containing macrocycles from readily accessible starting materials is presented. The first step comprises a chemoselective amidation of amino acid derived isocyanocarboxylicacid esters with unprotected symmetrical diamines to afford diverse α-isocyano-ω-amines. In the second step, the α-isocyano-ω-amines undergo
Abdelraheem, Eman M. M.; de Haan, Michel P.; Patil, Pravin; Kurpiewska, Katarzyna; Kalinowska-Tluscik, Justyna; Shaabani, Shabnam; Domling, Alexander   +7 more
openaire   +4 more sources

Probing Polar-π Interactions Between Tetrazoles and Aromatic Rings [PDF]

, 2023
The heterocyclic tetrazole, a well-established bioisosteric replacement of carboxylic acid, plays an important role in medicinal chemistry. To deepen the functional understanding of tetrazoles in chemical sciences, it is essential to investigate the ...
Jie Jian, Jasmin Mecinović, Bickelhaupt, F. Matthias, Jordi Poater, Mecinović, Jasmin, Paul Tinnemans, Jian, Jie, Tinnemans, Paul, Roel Hammink, Bickelhaupt, F Matthias, F. Matthias Bickelhaupt, Hammink, Roel, Poater, Jordi, Mecinović, Jasmin; id_orcid   +13 more
core   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +2 more sources

Alkylation of 5‑Substituted 1H‑Tetrazoles via the Diazotization of Aliphatic Amines

, 2021
A new alkylation reaction of monosubstituted tetrazoles via the diazotization of aliphatic amines is reported. This method enables preferential formation of 2,5-disubstituted tetrazoles. A one-pot 1,3-dipolar cycloaddition/diazotization sequence starting
Guillaume Reynard (11286297), Hélène Lebel (1392037)   +1 more
core   +2 more sources

Novel Therapeutic Approaches to Invasive Candidiasis: Considerations for the Clinician

Infection and Drug Resistance, 2023
Frederic Lamoth1,2 1Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; 2Institute of Microbiology, Department of Laboratory Medicine and Pathology, Lausanne University ...
Lamoth F
doaj  

Selective synthesis of 2-(1-methylvinyl)tetrazoles

, 1997
Hitherto unknown 2-(1-methylvinyl)tetrazoles have been obtained by regioselective alkylation of tetrazole and 5R-tetrazoles with 1-halogenopropan-2-ols and 3-bromopropene followed by dehydrohalogenation of the intermediate ...
Voitekhovich, S.V., Koren, A.O., Gaponik, P.N.   +2 more
core   +1 more source

α-Amino acid-isosteric α-amino tetrazoles [PDF]

, 2016
The synthesis of all 20 common natural proteinogenic and 4 otherα-amino acid-isosteric α-amino tetrazoles has been accomplished, whereby the carboxyl group is replaced by the isosteric 5-tetrazolyl group. The short process involves the use of the key Ugi
Dömling, Alexander, Herdtweck, Eberhardt, Zhao, Ting, Kalinowska-Tłuścik, Justyna, Kurpiewska, Katarzyna   +4 more
core   +2 more sources

Assessment of the potential risk of oteseconazole and two other tetrazole antifungals to inhibit adrenal steroidogenesis and peripheral metabolism of corticosteroids

Frontiers in Pharmacology
The triazole antifungals posaconazole and itraconazole can cause pseudohyperaldosteronism with hypertension and hypokalemia, edema, and gynecomastia by inhibiting steroid synthesis and metabolism.
Marie-Christin Jäger, Marie-Christin Jäger, Víctor González-Ruiz, Víctor González-Ruiz, Friedrich L. Joos, Friedrich L. Joos, Denise V. Winter, Julien Boccard, Julien Boccard, Thorsten Degenhardt, Steve Brand, Serge Rudaz, Serge Rudaz, George R. Thompson, Alex Odermatt, Alex Odermatt   +15 more
doaj   +1 more source