Results 21 to 30 of about 6,074 (218)

Synthesis of new bile acid-fused tetrazoles using the Schmidt reaction

Beilstein Journal of Organic Chemistry, 2021
A practical and high-yielding Schmidt reaction for the synthesis of fused tetrazoles from bile acid precursors was developed. Mild reaction conditions using TMSN3 instead of hydrazoic acid as an azide source produced good yields of the desired tetrazoles.
Dušan Đ. Škorić, Olivera R. Klisurić, Dimitar S. Jakimov, Marija N. Sakač, János J. Csanádi   +4 more
doaj   +1 more source

Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores

Molecules, 2022
N-(Aminoalkyl)azabicyclo[3.2.2]nonanes possess antiplasmodial and antitrypanosomal activity. A series with terminal tetrazole or sulfonamido partial structure was prepared. The structures of all new compounds were confirmed by NMR and IR spectroscopy and
Johanna Dolensky, Clemens Hinteregger, Andreas Leitner, Werner Seebacher, Robert Saf, Ferdinand Belaj, Pascal Mäser, Marcel Kaiser, Robert Weis   +8 more
doaj   +1 more source

Ultrasound-Assisted Ugi-Azide Multicomponent Reaction for the Synthesis of 1,5-Disubstituted Tetrazoles

Chemistry Proceedings, 2023
The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz, Sandra C. Ramírez-López, David Calderón-Rangel, Cristian Saldaña-Arredondo, Rocío Gámez-Montaño   +4 more
doaj   +1 more source

Metal-Free Regioselective N²‑Arylation of 1H‑Tetrazoles with Diaryliodonium Salts

, 2022
We describe a simple, metal-free regioselective N2-arylation strategy for 5-substituted-1H-tetrazoles with diaryliodonium salts to access 2-aryl-5-substituted-tetrazoles.
Raktim Abha Saikia (13113146), Ashim Jyoti Thakur (13113149), Anurag Dutta (11972124), Bipul Sarma (604086)   +3 more
core   +1 more source

Selective synthesis of ureas and tetrazoles from amides controlled by experimental conditions using conventional and microwave irradiation

Journal of Saudi Chemical Society, 2018
An efficient synthetic procedure has been achieved for selective synthesis of 1,5-disubstituted tetrazoles and diaryl ureas from secondary amides in situ in the presence of NaN3 and POCl3 as solvent, both by conventional and microwave methods.
Rajendran Sribalan, Andiappan Lavanya, Maruthan Kirubavathi, Vediappen Padmini   +3 more
doaj   +1 more source

Synthesis of New C- and N-β-d-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase

Molecules, 2018
The aim of the present study was to broaden the structure-activity relationships of C- and N-β-d-glucopyranosyl azole type inhibitors of glycogen phosphorylase.
Sándor Kun, Éva Bokor, Ádám Sipos, Tibor Docsa, László Somsák   +4 more
doaj   +1 more source

Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction

SynOpen, 2022
The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C in the presence of InCl3.
C. P. Irfana Jesin, Ramesh Kataria, Ganesh Chandra Nandi   +2 more
doaj   +1 more source

Synthesis and Properties of Dichlorovinyl Derivatives of Tetrazoles

, 2021
: 1-Substituted 1H-tetrazole-5-thiols and 5-substituted 1H-tetrazoles easily reacted with trichloroethylene to form the corresponding S- and N-dichlorovinyl derivatives, respectively.
Vorona, S.V., Ivashkevich, I.S., Lyakhov, A.S., Zevatskii, Yu.E., Myznikov, L.V.   +4 more
core   +1 more source

Synthesis, structure and characterisation of late transition metal complexes with 2-(tetrazol-1-yl)pyridine

Журнал Белорусского государственного университета: Химия, 2022
Complexes [MII(2-pytz)Cl2] (M(II) = Pt, Pd; 2-pytz = 2-(tetrazol-1-yl)pyridine) were synthesised via direct interaction of the corresponding metal chlorides (K2PtCl4 or PdCl2) with 2-pytz under ambient conditions.
Tatiyana V. Serebryanskaya, Hanna A. Belavusava, Yuri V. Grigoriev, Sergei V. Voitekhovich, Ludmila S. Ivashkevich, Oleg A. Ivashkevich   +5 more
doaj   +1 more source

Corrosion Inhibition of Copper in Non-polluted and Polluted Sea Water Using 5-phenyl-1-H-tetrazole

International Journal of Electrochemical Science, 2012
Corrosion inhibition of copper in salt water using 5-phenyl-1-H tetrazole (PTAH) was investigated. Experiments were also performed in salt water polluted with thiosulfate or sulfide ions.
F.M. Al Kharafi, I.M. Ghayad, R.M. Abdullah   +2 more
doaj   +1 more source