Results 21 to 30 of about 5,897 (227)

Generation of Sulfonylated Tetrazoles through an Iron-Catalyzed Multicomponent Reaction Involving Sulfur Dioxide

iScience, 2020
Summary: As a privileged motif, tetrazoles can be widely found in pharmaceuticals and materials science. Herein, a five-component reaction of cycloketone oxime esters, alkynes, DABCO·(SO2)2, and two molecules of trimethylsilyl azide under iron catalysis ...
Jun Zhang, Xuefeng Wang, Yunyan Kuang, Jie Wu   +3 more
doaj   +1 more source

Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2

Molecules, 2022
This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar moieties and modified analogues. All the newly synthesized derivatives were screened for their
Wael A. El-Sayed, Fahad M. Alminderej, Marwa M. Mounier, Eman S. Nossier, Sayed M. Saleh, Asmaa F. Kassem   +5 more
doaj   +1 more source

Photoinduced Porcine Gelatin Cross-Linking by Homobi- and Homotrifunctional Tetrazoles

Gels, 2021
Gelatin is a costless polypeptide material of natural origin, able to form hydrogels that are potentially useful in biomaterial scaffold design for drug delivery, cell cultures, and tissue engineering.
Luca Vaghi, Mauro Monti, Marcello Marelli, Elisa Motto, Antonio Papagni, Laura Cipolla   +5 more
doaj   +1 more source

Immobilization of La on THH-CO2H@Fe3O4 nanocomposite for the synthesis of one‐pot multicomponent reactions

Materials Research Express, 2021
The current research represents a facile and competent methodology in the development of a novel magnetic nanocatalyst. This composite was synthesized by immobilizing La on Fe _3 O _4 nanoparticles pre-functionalized with tetrahydroharman-3-carboxylic ...
Taiebeh Tamoradi, AfsanehTaheri Kal-Koshvandi, Bikash Karmakar, Ali Maleki   +3 more
doaj   +1 more source

6-(Tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as Novel Potent CK2 Inhibitors

Molecules, 2022
In this work, we describe the design, synthesis, and structure-activity relationship of 6-(tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as inhibitors of Casein kinase 2 (CK2).
Grigoriy V. Urakov, Konstantin V. Savateev, Svetlana K. Kotovskaya, Vladimir L. Rusinov, Alexandr A. Spasov, Denis A. Babkov, Elena V. Sokolova   +6 more
doaj   +1 more source

‘Atypical Ugi’ tetrazoles

Chemical Communications, 2020
We surprisingly found that combining the substrates of Ugi tetrazole reaction gives two different constitutional isomeric Ugi products A and B. A is the expected classical Ugi products whereas B is an isomeric product (‘atypical Ugi’).
Eman M. M. Abdelraheem, Imogen Goodwin, Shabnam Shaabani, Michel P. de Haan, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling   +6 more
openaire   +5 more sources

Ethyl 7-Acetyl-8a-methyl-3-(1-phenyl-1H-tetrazol-5-yl)-1,4,4a,5,6,8a-hexahydro-7H-pyrano[2,3-c]pyridazine-1-carboxylate

Molbank, 2022
The Diels–Alder reaction of ethyl 3-(1-phenyl-1H-tetrazol-5-yl-1,2-diaza-1,3-butadiene-1-carboxylate with 2-acetyl-6-methyl-2,3-dihydro-4H-pyran (methyl vinyl ketone dimer) regioselectively afforded the corresponding 3-(tetrazol-5-yl)-hexahydro-7H-pyrano[
Susana M. M. Lopes, Américo Lemos, José A. Paixão, Teresa M. V. D. Pinho e Melo   +3 more
doaj   +1 more source

Corrosion Inhibition of Copper in Non-polluted and Polluted Sea Water Using 5-phenyl-1-H-tetrazole

International Journal of Electrochemical Science, 2012
Corrosion inhibition of copper in salt water using 5-phenyl-1-H tetrazole (PTAH) was investigated. Experiments were also performed in salt water polluted with thiosulfate or sulfide ions.
F.M. Al Kharafi, I.M. Ghayad, R.M. Abdullah   +2 more
doaj   +1 more source

Tetrazole containing 1,5-benzothiazepines: Design, synthesis, in silico and in vitro evaluation as medicinally potent ACE inhibitors [PDF]

Journal of Chemistry Letters
It is reported in literature that the key role of Angiotensin-I Converting Enzyme (ACE) is to convert angiotensin-I (Ang-I) to angiotensin-II (Ang-II) and to degrade bradykinin (BK) into the inactive metabolites.
Bhawani Singh, Ashok Suman
doaj   +1 more source

3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents

Pharmaceuticals, 2022
Herein, the synthesis and anticancer activity evaluation of a series of novel β-carbolines is reported. The reactivity of nitrosoalkenes towards indole was explored for the synthesis of novel tryptophan analogs where the carboxylic acid was replaced by a
João L. P. Ribeiro, Joana B. Loureiro, Susana M. M. Lopes, Lucília Saraiva, Teresa M. V. D. Pinho e Melo   +4 more
doaj   +1 more source