Results 21 to 30 of about 18,306 (270)
The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz +4 more
doaj +1 more source
X-Ray, IR, NMR, UV-visible spectra and DFT analysis of 5-aryloxy-(1H)-tetrazoles, structure, conformation and tautomerism [PDF]
The predominant tautomeric forms of N1–H, N2–H of 5-(2,6-dimethyl- and 5-(2,6-diisopropylphenoxy)-(1H)-tetrazoles were analyzed at B3LYP method using 6-311G(d,p) basis set in the gas phase.
Alireza Dadrass +8 more
core +1 more source
Refinement of Copper(II) Azide with 1‐Alkyl‐5H‐tetrazoles: Adaptable Energetic Complexes
A concept for stabilizing highly sensitive and explosive copper(II) azide with 1‐N‐substituted tetrazoles is described. It was possible to stabilize the system by the use of highly endothermic, nitrogen‐rich ligands.
Maximilian H. H. Wurzenberger +4 more
semanticscholar +1 more source
Indium-Mediated Cleavage of the Trityl Group from Protected 1H-Tetrazoles [PDF]
On treatment with indium metal in MeOH–THF, trityl groups undergo reductive removal from 1H-protected tetrazoles (including aliphatic, aromatic, and heteroaromatic substituents), affording the corresponding free tetrazoles in excellent yields, without ...
Behloul, Cherif +5 more
core +2 more sources
Greener Selective Cycloalkane Oxidations with Hydrogen Peroxide Catalyzed by Copper-5-(4-pyridyl)tetrazolate Metal-Organic Frameworks [PDF]
Microwave assisted synthesis of the Cu(I) compound [Cu(µ4-4-ptz)]n [1, 4-ptz = 5-(4-pyridyl)tetrazolate] has been performed by employing a relatively easy method and within a shorter period of time compared to its sister compounds.
Martins, Luisa +5 more
core +6 more sources
Synthesis of N-Fmoc-ProtectedAmino Alkyl Thiocyanates/Selenocyanates and their Applicationin the Preparation of 5-Substituted S/Se-Linked Tetrazoles [PDF]
A novel class of N-Fmoc-protected amino alkyl thiocy- anates/selenocyanates has been prepared by thiocyanation/seleno-cyanation of the corresponding alkyl iodides. These thiocyanates/selenocyanates undergo a facile [2+3]-cycloaddition reaction
Basavalingappa, P. Vasantha +2 more
core +1 more source
An efficient synthetic procedure has been achieved for selective synthesis of 1,5-disubstituted tetrazoles and diaryl ureas from secondary amides in situ in the presence of NaN3 and POCl3 as solvent, both by conventional and microwave methods.
Rajendran Sribalan +3 more
doaj +1 more source
Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction
The sulfoximine-based tetrazoles have been synthesized via azido-Ugi four-component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 °C in the presence of InCl3.
C. P. Irfana Jesin +2 more
doaj +1 more source
Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor [PDF]
Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad substrate scope.
Jamison, Timothy F., Palde, Prakash B.
core +1 more source
The aim of the present study was to broaden the structure-activity relationships of C- and N-β-d-glucopyranosyl azole type inhibitors of glycogen phosphorylase.
Sándor Kun +4 more
doaj +1 more source

