Results 11 to 20 of about 6,074 (218)

Electrostatic Activation of Tetrazoles [PDF]

open access: yesThe Journal of Organic Chemistry, 2020
Photoactivation of tetrazoles to form nitrile imines primed for 1,3-dipolar cycloaddition reactions is of widespread utility in chemistry. In contrast, the corresponding thermal reactions usually possess prohibitively high barriers and have garnered significantly less attention.
Vincent Doan   +2 more
openaire   +5 more sources

Multi-Gram Synthesis of Enantiopure 1,5-Disubstituted Tetrazoles Via Ugi-Azide 3-Component Reaction

open access: yesMolecules, 2018
Tetrazoles have been widely studied for their biological properties. An efficient route for large-scale synthesis of 1,5-disubstituted tetrazoles (1,5-DTs) is presented.
Pietro Capurro   +4 more
doaj   +2 more sources

TADF-Active Tetrazole Luminophores for Visible-Light Functionalization of Nanoparticles and Surfaces. [PDF]

open access: yesAngew Chem Int Ed Engl
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Hojo R   +11 more
europepmc   +3 more sources

Tetrazoles: a new class of compound for crystallization modification [PDF]

open access: yes, 2010
Tetrazoles are a class of organic compound often used as carboxylic acid analogues. This analogous behaviour is shown to extend to crystallization modification, that is, tetrazoles are also able to influence crystal growth and morphology although in a ...
Franca Jones (1838584)   +3 more
core   +2 more sources

Alkylation of 5‑Substituted 1H‑Tetrazoles via the Diazotization of Aliphatic Amines

open access: yes, 2021
A new alkylation reaction of monosubstituted tetrazoles via the diazotization of aliphatic amines is reported. This method enables preferential formation of 2,5-disubstituted tetrazoles. A one-pot 1,3-dipolar cycloaddition/diazotization sequence starting
Guillaume Reynard (11286297)   +1 more
core   +2 more sources

6-(Tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as Novel Potent CK2 Inhibitors

open access: yesMolecules, 2022
In this work, we describe the design, synthesis, and structure-activity relationship of 6-(tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as inhibitors of Casein kinase 2 (CK2).
Grigoriy V. Urakov   +6 more
doaj   +1 more source

Immobilization of La on THH-CO2H@Fe3O4 nanocomposite for the synthesis of one‐pot multicomponent reactions

open access: yesMaterials Research Express, 2021
The current research represents a facile and competent methodology in the development of a novel magnetic nanocatalyst. This composite was synthesized by immobilizing La on Fe _3 O _4 nanoparticles pre-functionalized with tetrahydroharman-3-carboxylic ...
Taiebeh Tamoradi   +3 more
doaj   +1 more source

Ethyl 7-Acetyl-8a-methyl-3-(1-phenyl-1H-tetrazol-5-yl)-1,4,4a,5,6,8a-hexahydro-7H-pyrano[2,3-c]pyridazine-1-carboxylate

open access: yesMolbank, 2022
The Diels–Alder reaction of ethyl 3-(1-phenyl-1H-tetrazol-5-yl-1,2-diaza-1,3-butadiene-1-carboxylate with 2-acetyl-6-methyl-2,3-dihydro-4H-pyran (methyl vinyl ketone dimer) regioselectively afforded the corresponding 3-(tetrazol-5-yl)-hexahydro-7H-pyrano[
Susana M. M. Lopes   +3 more
doaj   +1 more source

‘Atypical Ugi’ tetrazoles

open access: yesChemical Communications, 2020
We surprisingly found that combining the substrates of Ugi tetrazole reaction gives two different constitutional isomeric Ugi products A and B. A is the expected classical Ugi products whereas B is an isomeric product (‘atypical Ugi’).
Eman M. M. Abdelraheem   +6 more
openaire   +5 more sources

Mechanistic DFT Study of 1,3-Dipolar Cycloadditions of Azides with Guanidine

open access: yesMolecules, 2023
Density functional calculations SMD(chloroform)//B3LYP/6-311+G(2d,p) were employed in the computational study of 1,3-dipolar cycloadditions of azides with guanidine.
Ivana Antol   +2 more
doaj   +1 more source

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