Results 81 to 90 of about 5,897 (227)
In Vitro Studies of Chromone-Tetrazoles against Pathogenic Protozoa, Bacteria, and Fungi
Molecules, 2015 In vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (Entamoeba histolytica), pathogenic bacteria (Pseudomonas aeruginosa, and Staphylococcus aureus)
Pedro A. Cano +8 more
doaj +1 more source
Synthesis and Functionalization of 5-Substituted Tetrazoles
, 2010 In the last decades, the chemistry of tetrazoles underwent a great expansion, which was closely connected with their usage as an isosteric replacement of carboxylic acid moiety in the molecules of potential or clinically used drugs.
Roh, Jaroslav
core
Synthesis of tetrazoles as anticuberculotics [PDF]
, 2014 Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Candidate: Petr Vicherek Supervisor: RNDr. Patrik Čonka, Ph.D. Title of diploma thesis: Synthesis of tetrazoles as antituberculotics Although
Vicherek, Petr
core
Israel Journal of Chemistry, Volume 66, Issue 5, September 2026.The Gram‐positive bacteria, Staphylococcus aureus, contain wall teichoic acid (WTA, a glycopolymer (green and yellow)) is a virulence factor in their cell wall. Synthesis of the peptidoglycan‐(PG)‐WTA conjugate (blue squares) was developed via the phospho‐donor and PG acceptor (structures at the bottom right).
Min Liu +2 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.A series of ten 5,5′‐azotetrazolate salts with nitrogen‐rich bases is prepared and assessed as technologically accessible gas‐generating materials. Structural, safety, and ballistic evaluations reveal several compounds combining high bulk density, acceptable sensitivities, and favorable gas‐generation performance, highlighting the potential of ...
Adam Votýpka +8 more
wiley +1 more source
Synthesis, single crystal analysis, biological and docking evaluation of tetrazole derivatives
Heliyon, 2018 Tetrazoles are conjugated nitrogen-rich heterocycles considered as bio-isosteres of carboxylic acids. Tetrazoles owing to their conjugated structures serve as biologically relevant potent scaffolds.
Hamid Aziz +4 more
doaj +1 more source
, 1999 The synthesis of tetrazoles derived from D-manno and D- rhamnopyranose from L-gulonolactone and of L-rhamnopyranose from D-gulonolactone is described. These and other materials are assessed as inhibitors of glycosidases. The [4.3.0] tetrazoles of D-manno-
Hackett, L +10 more
core +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 3, September 2026.The synthesized compounds exhibited excellent cytotoxicity on MCF‐7, breast cancer cell line with selective profile especially 2d with IC50 value of 0.12 μM. Three compounds 2c, 2d, and 2h caused almost as much apoptosis induction as cisplatin. Compound 2d exhibited caspase‐3 activation at standard drug level.
Zeynep Zişan Demirci +3 more
wiley +1 more source
Journal of Chemistry, 2013 Silica sulfuric acid (SSA) was found to be an efficient heterogeneous catalyst for the synthesis of 1-substituted 1H-1,2,3,4-tetrazoles from the reaction of primary amines with triethyl orthoformate and sodium azide under thermal and solvent-free ...
Davood Habibi +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 16, 27 August 2026.Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti +10 more
wiley +1 more source