Results 201 to 210 of about 17,991 (268)

Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway. [PDF]

open access: yesJ Med Chem
Karabanovich G   +14 more
europepmc   +1 more source
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Tetrazoles for biomedicine

Russian Chemical Reviews, 2019
The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents.
E. A. Popova   +3 more
openaire   +3 more sources

Metal-Free Regioselective N2-Arylation of 1H-Tetrazoles with Diaryliodonium Salts.

Journal of Organic Chemistry, 2022
We describe a simple, metal-free regioselective N2-arylation strategy for 5-substituted-1H-tetrazoles with diaryliodonium salts to access 2-aryl-5-substituted-tetrazoles.
R. Saikia   +3 more
semanticscholar   +1 more source

Intensified Continuous Flow Synthesis and Workup of 1,5-Disubstituted Tetrazoles Enhanced by Real-Time Process Analytics

, 2021
Continuous flow processing presents a solution for the safe and effective formation of 1,5-tetrazoles due to the small reactive inventory and absence of a reactor headspace.
Peter Sagmeister   +7 more
semanticscholar   +1 more source

Tetrazoles: XLVII. A route to tetrazole-containing dendrimers [PDF]

open access: possibleRussian Journal of Organic Chemistry, 2004
The reaction of 5-methylsulfonyl-1-phenyltetrazole with pentaerythritol in acetonitrile in the presence of sodium hydroxide gave tetrakis(1-phenyltetrazol-5-yloxymethyl)methane. Sulfur-containing analog of the latter was obtained by alkylation of 1-phenyl-4,5-dihydrotetrazole-5-thione with 1,3-dibromo-2,2-bis-(bromomethyl)propane.
G. I. Koldobskii   +2 more
openaire   +1 more source

Protolytic Equilibria in Tetrazoles [PDF]

open access: possibleChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
R. E. Trifonov, V. A. Ostrovskii
openaire   +2 more sources

Nitroimino-tetrazolates and Oxy-nitroimino-tetrazolates

Journal of the American Chemical Society, 2010
Highly energetic 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazolate) salts were obtained by reacting equimolar quantities of the acidic 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazole) and energetic bases in aqueous solution. Additionally, metathesis of silver 1,1'-ethylenebis(oxy)bis(5-nitroimino-tetrazolate) with diaminoguanidinium chloride or ...
Young-Hyuk Joo, Jean'ne M. Shreeve
openaire   +3 more sources

Recent Developments in the Synthesis of Tetrazoles and their Pharmacological Relevance

Current organic chemistry, 2020
The heterocycle ring tetrazole is an important moiety relevant to medicinal chemistry since it is present in some drugs with clinical importance. Its primary biological activity is being a bioisosteric analogue of the carboxylic acid and cis-amide ...
S. Leyva‐Ramos, Jaime Cardoso-Ortiz
semanticscholar   +1 more source

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