Results 91 to 100 of about 10,686 (159)

Synthesis and Evaluation of Aromatic Sulfonamide and Disulfonamide Derivatives as Dengue Virus NS3–NS5 Interaction Inhibitors

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč, Jan Drahorád, Jakub Harvalík, Tereza Horáčková, Manfred Brinker, Arianna Loregian, Andrea Brancale, Beatrice Mercorelli, Petra Cuřínová   +8 more
wiley   +1 more source

The solvent extraction and spectrophotometric determination of vanadium (V) with 4-(2-thiazolylazo)resorcinol and tetrazolium salts

Open Chemistry, 2007
Gavazov Kiril, Lekova Vanya, Dimitrov Atanas, Patronov Georgi   +3 more
doaj   +1 more source

In Vitro Biological Activities of Piper corcovadensis C.DC.: Antioxidant, Antineoplastic‐Related and Antibacterial Effects

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Piper corcovadensis extract is rich in bioactive compounds with antioxidant potential, capable of decreasing ROS levels; antitumor activity in cutaneous melanoma cells SK‐MEL‐28; and anti‐inflammatory activity, decreasing the expression of IL‐6 and NLPR3 genes and increasing TNF expression, without cytotoxicity to healthy peripheral blood cells (PBMCs).
Bruno Henrique Fontoura, Ellen Cristina Perin, Margarete Dulce Bagatini, Daiane Manica, Gilnei Bruno da Silva, Michelle Fernanda Faita Rodrigues, José Abramo Marchese, Solange Teresinha Carpes   +7 more
wiley   +1 more source

Britannilactone 1-O-acetate induced ubiquitination of NLRP3 inflammasome through TRIM31 as a protective mechanism against reflux esophagitis-induced esophageal injury

Chinese Medicine
Background Reflux esophagitis (RE) is a disease in which inflammation of the esophageal mucosa owing to the reflux of gastric contents into the esophagus results in cytokine damage.
Ju Liu, Yang Xiao, Qianfei Xu, Yunyan Xu, Manman Guo, Yun Hu, Yan Wang, Yi Wang   +7 more
doaj   +1 more source

Tetrazolylidene-Stabilized Gold(I) Complexes: Synthesis and Evaluation of Anticancer Activity <i>In Vitro</i>. [PDF]

Inorg Chem
Stifel S, Schmidt C, Richter LF, Pöthig A, Casini A, Kühn FE.   +5 more
europepmc   +1 more source

Rezafungin exhibits anti-biofilm properties against fungal biofilms in vitro. [PDF]

J Antimicrob Chemother
Abduljalil H, Bartie K, Bal AM, Bal AM, Rautemaa-Richardson R, Williams C, Kean R, Ramage G.   +7 more
europepmc   +1 more source

Silver-<i>N</i>-Heterocyclic Complexes Against <i>Leishmania major</i>: In Vitro, In Vivo and In Silico Therapeutic Activities. [PDF]

Pharmaceuticals (Basel)
Şahin N, Polat ZA, Gülpınar DG, Ataş AD, Üstün E, Özdemir İ, Sémeril D.   +6 more
europepmc   +1 more source

Toxic or non-toxic: a critical assessment of the contradictory results for selected graphene family materials. [PDF]

Front Toxicol
Andraos C, Wepener V, Gulumian M.
europepmc   +1 more source

What a Difference a Water Molecule Makes-A Combined Experimental/Theoretical Study on 2,3,5-triphenyl-2<i>H</i>-tetrazol-3-ium Chloride Hydrate in Solution and the Solid-State. [PDF]

Molecules
Bechaieb R, El-Tohamy MF, AlRabiah H, Mostafa GAE, E Silva BP, Niazi M, Klein A.   +6 more
europepmc   +1 more source

Save Your Tears for the Toxicity Assays-Carbon Nanotubes Still Fooling Scientists. [PDF]

ACS Omega
Suni J, Valkama S, Peltola E.
europepmc   +1 more source