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[Quantitative determination of tetrodotoxin in poisoned biological samples by two-dimensional liquid chromatography-tandem mass spectrometry]. [PDF]
Se PuFang L, Qiu FM, Wang YC.
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The American Journal of Emergency Medicine, 2003
Tetrodotoxin (TTX) poisoning, although uncommon, is frequently seen in Taiwan, Japan, and Southeast Asia. It is rare but significant in the United States as well. Only three cases have been reported in the EM literature. We report an outbreak of six cases of TTX poisoning from eating puffer fish. On April 17, 2001, an outbreak of TTX poisoning occurred
Chorng-Kuang, How +4 more
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Tetrodotoxin (TTX) poisoning, although uncommon, is frequently seen in Taiwan, Japan, and Southeast Asia. It is rare but significant in the United States as well. Only three cases have been reported in the EM literature. We report an outbreak of six cases of TTX poisoning from eating puffer fish. On April 17, 2001, an outbreak of TTX poisoning occurred
Chorng-Kuang, How +4 more
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2007
Tetrodotoxin (TTX) is one of the most potent and oldest known neurotoxins. The poisoning cases due to ingestion of TTX-containing marine animals, especially for puffer, have frequently occurred in Asia since a long time ago. This chapter describes various topics on TTX poisoning including the tendency of poisoning incidents, typical case report ...
Deng-Fwu, Hwang, Tamao, Noguchi
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Tetrodotoxin (TTX) is one of the most potent and oldest known neurotoxins. The poisoning cases due to ingestion of TTX-containing marine animals, especially for puffer, have frequently occurred in Asia since a long time ago. This chapter describes various topics on TTX poisoning including the tendency of poisoning incidents, typical case report ...
Deng-Fwu, Hwang, Tamao, Noguchi
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The world of food safety is a complex tapestry, woven together by various contaminants and hazards that can compromise consumer well-being. Among these, tetrodotoxin (TTX) stands out as a potent and potentially lethal neurotoxin found in certain marine creatures, notably the pufferfish.
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11-Oxo-tetrodotoxin and a specifically labelled 3H-Tetrodotoxin
Toxicon, 1996Tetrodotoxin was oxidized to a hydrated aldehyde, 11-oxo-tetrodotoxin, which shares the specificity of tetrodotoxin for the Na+ channel of the isolated voltage-clamped frog skeletal muscle fiber, but is four to five times more potent. It binds to the solubilized Na+ channel of eel electroplax with a similarly higher potency, because of an equilibrium ...
B Q, Wu +5 more
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Total Synthesis of Tetrodotoxin
Angewandte Chemie International Edition, 2020AbstractA total synthesis of tetrodotoxin was accomplished. A Diels–Alder reaction between a known enone and a siloxy diene gave a tricyclic product, the steric bias of which was used to construct the remaining stereogenic centers. A nitrogen atom was introduced either by a four‐step sequence involving a Curtius rearrangement, or a three‐step sequence ...
Keigo Murakami +3 more
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Tetrodotoxin and neuromuscular transmission
Proceedings of the Royal Society of London. Series B. Biological Sciences, 19671. The puffer fish poison, tetrodotoxin ( T . T .) was applied to eliminate impulse propagation in nerve and muscle fibre, and the physiological properties of the neuromuscular junction were studied under this condition. 2.
B, Katz, R, Miledi
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