Results 71 to 80 of about 26,870 (181)

Reconsidering the role of introduced species in the climate‐affected and highly invaded eastern Mediterranean

Conservation Biology, EarlyView.
Abstract Bioinvasions are considered mostly as a biodiversity and conservation hazard, but in specific situations, introduced species can bring ecological or socioeconomic benefits. We assessed the social–ecological role of marine introduced species in the eastern Mediterranean Sea—a global hotspot of bioinvasions and extirpations—and their potential ...
Stelios Katsanevakis, Jonathan Belmaker, Gil Rilov, Erez Yeruham, Andreas Konstantinidis, Maria Papazekou, Sylvaine Giakoumi, Antonios D. Mazaris   +7 more
wiley   +1 more source

New Gastropod Vectors and Tetrodotoxin Potential Expansion in Temperate Waters of the Atlantic Ocean

Marine Drugs, 2012
Tetrodotoxin is a potent low weight marine toxin found in warm waters, especially of the Indian and Pacific Oceans. Intoxications are usually linked to the consumption of the puffer fish, although TTX was already detected in several different edible taxa.
Vítor Vasconcelos, Amparo Alfonso, Luis M. Botana, Joana Azevedo, Paula Rodriguez, Marisa Silva   +5 more
doaj   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend The lateral hypothalamus (LH) is a critical controller of innate behaviours such as feeding. It is anatomically connected to specific cortical areas. We mapped these areas using a combination of retrograde tracing and anterograde optogenetic circuit mapping.
Lotte J. A. M. Razenberg, Pieter Nicolaas de Greef, Huibert D. Mansvelder, Mahesh Miikael Karnani   +3 more
wiley   +1 more source

Oxidative stress and hepatotoxicity in rats induced by poisonous pufferfish (Lagocephalus lagocephalus) meat

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
This study was undertaken to evaluate the effect of pufferfish (Lagocephalus lagocephalus) meat poisoning on hepatic functions of Wistar rats. For this purpose, groups of rats (Lcr, Lcu+b and Lcu-b) received diet supplemented with 10% of raw or cooked ...
M Saoudi, A Abdelmouleh, F Ellouze, K Jamoussi, A El Feki   +4 more
doaj   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Biomedical and pharmacological potential of tetrodotoxin-producing bacteria isolated from marine pufferfish Arothron hispidus (Muller, 1841)

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Specimens of the pufferfish Arothron hispidus collected at Parangipettai, on the southeast coast of India, were subjected to bacterial isolation and identification.
S Bragadeeswaran, D Therasa, K Prabhu, K Kathiresan   +3 more
doaj   +1 more source

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

The Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang, Pabitra Hriday Patra, Jinquan Yang   +2 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

The Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu, Eduardo Bravo, George Bradley Richerson   +2 more
wiley   +1 more source