Risks for public health related to the presence of tetrodotoxin (TTX) and TTX analogues in marine bivalves and gastropods. [PDF]
EFSA J, 2017 Peer reviewedPublisher ...
EFSA Panel on Contaminants in the Food Chain (CONTAM) +30 more
europepmc +12 more sources
Tetrodotoxin (TTX) as a Therapeutic Agent for Pain [PDF]
Marine Drugs, 2012 Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions.
Cruz Miguel Cendán +5 more
doaj +6 more sources
Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]
Marine Drugs, 2015 Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Lauren R. Salvitti +3 more
doaj +6 more sources
Diversity and Biosynthetic Potential of Culturable Microbes Associated with Toxic Marine Animals [PDF]
Marine Drugs, 2013 Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Brett A. Neilan +3 more
doaj +4 more sources
Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata [PDF]
Marine Drugs, 2013 The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor +6 more
doaj +3 more sources
No Evidence for a Culturable Bacterial Tetrodotoxin Producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida) [PDF]
Toxins, 2015 Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Lauren R. Salvitti +3 more
doaj +4 more sources
An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens) Efts and Adults [PDF]
Journal of Toxicology, 2018 We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults.
Mackenzie M. Spicer +5 more
doaj +2 more sources
Marine Drugs, 2023 Gymnodimine D (GYM D), 16-desmethyl gymnodimine D (16-desmethyl GYM D), and two tetrodotoxin analogues have been found in invertebrates obtained from the north Atlantic coast of Spain from May 2021 to October 2022.
Araceli E. Rossignoli +3 more
doaj +1 more source
Confirmation and distribution of tetrodotoxin for the first time in terrestrial invertebrates: two terrestrial flatworm species (Bipalium adventitium and Bipalium kewense). [PDF]
PLoS ONE, 2014 The potent neurotoxin tetrodotoxin (TTX) is known from a diverse array of taxa, but is unknown in terrestrial invertebrates. Tetrodotoxin is a low molecular weight compound that acts by blocking voltage-gated sodium channels, inducing paralysis. However,
Amber N Stokes +7 more
doaj +1 more source
Marine Drugs, 2021 Most marine biotoxins are produced by microalgae. The neurotoxin tetrodotoxin (TTX) has been reported in many seafood species worldwide but its source is unknown, making accumulation and depuration studies in shellfish difficult.
Laura Biessy +6 more
doaj +1 more source