Results 11 to 20 of about 19,032 (194)

Investigating Diet as the Source of Tetrodotoxin in Pleurobranchaea maculata

Marine Drugs, 2013
The origin of tetrodotoxin (TTX) is highly debated; researchers have postulated either an endogenous or exogenous source with the host accumulating TTX symbiotically or via food chain transmission.
Serena Khor, Susanna A. Wood, Lauren Salvitti, David I. Taylor, Janet Adamson, Paul McNabb, Stephen Craig Cary   +6 more
doaj   +3 more sources

Intracellular Immunohistochemical Detection of Tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria) [PDF]

Marine Drugs, 2015
Tetrodotoxin (TTX), is a potent neurotoxin targeting sodium channels that has been identified in multiple marine and terrestrial organisms. It was recently detected in the Opisthobranch Pleurobranchaea maculata and a Platyhelminthes Stylochoplana sp ...
Lauren R. Salvitti, Susanna A. Wood, Leigh Winsor, Stephen Craig Cary   +3 more
doaj   +2 more sources

Tetrodotoxin Concentrations in Pleurobranchaea maculata: Temporal, Spatial and Individual Variability from New Zealand Populations

Marine Drugs, 2012
Tetrodotoxin (TTX) is a potent neurotoxin that has been identified in a range of phylogenetically unrelated marine and terrestrial organisms. Tetrodotoxin was recently detected in New Zealand in Pleurobranchaea maculata (the grey side-gilled sea slug ...
Stephen Craig Cary, Susanna A. Wood, Janet Adamson, Paul McNabb, Jarrod Walker, David I. Taylor   +5 more
doaj   +2 more sources

Diversity and Biosynthetic Potential of Culturable Microbes Associated with Toxic Marine Animals

Marine Drugs, 2013
Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Brett A. Neilan, Susanna A. Wood, John A. Kalaitzis, Rocky Chau   +3 more
doaj   +2 more sources

No Evidence for a Culturable Bacterial Tetrodotoxin Producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida)

Toxins, 2015
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Lauren R. Salvitti, Susanna A. Wood, Paul McNabb, Stephen Craig Cary   +3 more
doaj   +2 more sources

Tissue accumulation of tetrodotoxin (TTX) and analogues in trumpet shell Charonia lampas

Food Additives & Contaminants: Part A, 2022
Tetrodotoxin (TTX) is a potent neurotoxin responsible for a human intoxication event in Spain associated with the consumption of trumpet shell Charonia lampas. In Europe, TTX is not regulated or monitored, and there is little knowledge about its presence in seafood.
Lage, Sandra, Afonso, Inês I., Reis Costa, Pedro, Canário, Adelino V. M., Da Silva, José P.   +4 more
openaire   +5 more sources

The toxic mechanism and application of tetrodotoxin (TTX) [PDF]

MATEC Web of Conferences
Tetrodotoxin (TTX) is a powerful toxin related to nerve cells that is commonly discovered at loads of puffer fish, and working out the best way of cooking, whereas keeping the flavour but getting rid of the toxicity has challenged people for decades, which removing the organ with toxin is currently most certified.
Zhang Xiaonan, Xiaonan Zhang
openaire   +3 more sources

Seasonal and Spatial Variations in Bacterial Communities From Tetrodotoxin-Bearing and Non-tetrodotoxin-Bearing Clams [PDF]

Frontiers in Microbiology, 2020
Tetrodotoxin (TTX) is one of the most potent naturally occurring compounds and is responsible for many human intoxications worldwide. Paphies australis are endemic clams to New Zealand which contain varying concentrations of TTX. Research suggests that P.
Laura Biessy, Laura Biessy, Laura Biessy, John K. Pearman, Kirsty F. Smith, Ian Hawes, Susanna A. Wood   +6 more
doaj   +2 more sources

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons. [PDF]

The Journal of biological chemistry, 2004
The microO-conotoxins are an intriguing class of conotoxins targeting various voltage-dependent sodium channels and molluscan calcium channels. In the current study, we have shown MrVIA and MrVIB to be the first known peptidic inhibitors of the transient tetrodotoxin-resistant (TTX-R) Na(+) current in rat dorsal root ganglion neurons, in addition to ...
Daly, N., Ekberg, J.A., Thomas, L., Adams, D.J., Lewis, R.J., Craik, D.J.   +5 more
openaire   +6 more sources

Toxic mechanism and detection methods of tetrodotoxin [PDF]

MATEC Web of Conferences
Tetrodotoxin (TTX) was first isolated in the early 20th century and has significant public health implications, especially in areas where puffer fish are consumed, such as Japan.
Xu Yunzhe
doaj   +2 more sources