Results 41 to 50 of about 27,116 (203)

Isolation and Identification of a New Tetrodotoxin-Producing Bacterial Species, Raoultella terrigena, from Hong Kong Marine Puffer Fish Takifugu niphobles

Marine Drugs, 2011
Puffer fish, Takifugu niphobles, collected from the Hong Kong coastal waters were screened for tetrodotoxin-producing bacteria. A Gram-negative, non-acid-fast, non-sporing and rod shaped bacterial strain (designated as gutB01) was isolated from the ...
Fred Wang-Fat Lee, Peter Hoi-Fu Yu, Vincent Chung-Him Yu, Kin-Chung Ho   +3 more
doaj   +1 more source

Structures of mu O-conotoxins from Conus marmoreus - Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons [PDF]

, 2004
The muO-conotoxins are an intriguing class of conotoxins targeting various voltage-dependent sodium channels and molluscan calcium channels. In the current study, we have shown MrVIA and MrVIB to be the first known peptidic inhibitors of the transient ...
Thomas, L., L. Daly, Norelle, Daly, NL, Craik, D. J., Adams, D. J., Adams, D.J., J. Craik, David, Ekberg, J.A., Ekberg, Jenny, Lewis, R. J., Lewis, RJ, Craik, D.J., Adams, Denise, Craik, DJ, Ekberg, JA, Adams, DJ, Lewis, R.J., J. Adams, David, Ekberg, J. A., J. Lewis, Richard, Daly, N. L., Daly, N., Thomas, Linda, Lewis, Richard J., A. Ekberg, Jenny, Thomas, L, Daly, Norelle L., Craik, David   +27 more
core   +1 more source

Prostaglandin E2 Has No Effect on Two Components of Tetrodotoxin-Resistant Na+ Current in Mouse Dorsal Root Ganglion

Journal of Pharmacological Sciences, 2007
One possible mechanism underlying inflammation-induced sensitization of the primary afferent neuron is the upregulation of tetrodotoxin-resistant (TTX-R) Na+ current by inflammatory mediators such as prostaglandins.
Taixing Zheng, Jun-ichi Kakimura, Tomoya Matsutomi, Chizumi Nakamoto, Nobukuni Ogata   +4 more
doaj   +1 more source

Does Ocean Sunfish Mola spp. (Tetraodontiformes: Molidae) Represent a Risk for Tetrodotoxin Poisoning in the Portuguese Coast?

Marine Drugs, 2022
Tetrodotoxin (TTX) is a potent neurotoxin naturally occurring in terrestrial and marine organisms such as pufferfish. Due to the risk of TTX poisoning, fish of Tetraodontidae family and other puffer-related species must not be placed in the EU markets ...
Miguel Baptista, Ana Catarina Braga, Rui Rosa, Pedro Reis Costa   +3 more
doaj   +1 more source

Tetrodotoxin functions as a stress relieving substance in juvenile tiger puffer Takifugu rubripes [PDF]

, 2019
We tested whether tetrodotoxin (TTX) functions as a stress relieving substance in puffer fish. We orally administered TTX to the juveniles of hatchery-reared non-toxic tiger puffer Takifugu rubripes and measured the effects of TTX on brain corticotropin ...
Arakawa, Osamu, Sakakura, Yoshitaka, Takaoka, Minami, Takatani, Tomohiro, Amiya, Noriko, Amano, Masafumi, Sato, Haruka   +6 more
core   +1 more source

Safety, Tolerability, Pharmacokinetics, and Concentration-QTc Analysis of Tetrodotoxin: A Randomized, Dose Escalation Study in Healthy Adults

Toxins, 2020
Tetrodotoxin (TTX) is a highly specific voltage-gated sodium channel (VGSC) blocker in clinical evaluation as a peripheral-acting analgesic for chronic pain. This study presents the first published results of the safety including cardiac liability of TTX
Mojgan Kavoosi, Terry E. O’Reilly, Mehran Kavoosi, Peng Chai, Caroline Engel, Walter Korz, Christopher C. Gallen, Robert M. Lester   +7 more
doaj   +1 more source

Chronic In Vivo Effects of Repeated Exposure to Low Oral Doses of Tetrodotoxin: Preliminary Evidence of Nephrotoxicity and Cardiotoxicity

Toxins, 2019
Tetrodotoxin (TTX) is one of the most potent naturally occurring neurotoxins. Initially TTX was associated with human food intoxications in Japan, but nowadays, concerns about the human health risks posed by TTX have increased in Europe after the ...
Andrea Boente-Juncal, Carmen Vale, Manuel Cifuentes, Paz Otero, Mercedes Camiña, Mercedes Rodriguez-Vieytes, Luis Miguel Botana   +6 more
doaj   +1 more source

Isolation, Identification, and Characterization of Tetrodotoxin Producing Bacillus amyloliquefaciens B1 Originated from Carcinoscorpius rotundicauda [PDF]

, 2023
This study isolated and identified Bacillus amyloliquefaciens B1 from Carcinoscorpius rotundicauda by carrying out the 16S rRNA sequence analysis, reconstructing the phylogenetic tree based on the Environment for Tree Exploration (ETE3) v3.1.1 belonging ...
Tu Ho, Canh Le, Phong Le, Yen Tran, Tu Nguyen, Phuc Hua, Tra Doan, Bao Phan   +7 more
core   +1 more source

Behavioral and Chemical Ecology of Marine Organisms with Respect to Tetrodotoxin

Marine Drugs, 2010
The behavioral and chemical ecology of marine organisms that possess tetrodotoxin (TTX) has not been comprehensively reviewed in one work to date. The evidence for TTX as an antipredator defense, as venom, as a sex pheromone, and as an attractant for TTX-
Becky L. Williams
doaj   +1 more source

Gustatory Detection of Tetrodotoxin and Saxitoxin, and Its Competitive Inhibition by Quinine and Strychnine in Freshwater Fishes

Marine Drugs, 2011
Fish detect extremely low levels of marine toxins tetrodotoxin (TTX) and saxitoxin (STX) via the specialized gustatory receptor(s). Physiological and pharmacological studies show that receptor(s) for TTX and STX are distinct from those which detect ...
Toshiaki J. Hara
doaj   +1 more source