Results 111 to 120 of about 10,876 (160)

Serotonin engages divergent 5‐HT receptor pathways for cell type‐resolved modulation of prefrontal layer 5 microcircuits

British Journal of Pharmacology, Volume 183, Issue 19, Page 5832-5853, October 2026.
Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama, Guanxiao Qi, Gabriele Radnikow, Danqing Yang, Dirk Feldmeyer   +4 more
wiley   +1 more source

Functional Constraints and the Evolution of TTX-resistance in TTX-bearing Salamanders [PDF]

, 2013
Tetrodotoxin (TTX) binds to voltage-gated sodium (NaV) channels, blocking the initiation of action potentials and the activity of nerve and muscle fibers. Some salamanders use TTX as an anti-predator defense.
Haslem, Angela
core   +1 more source

Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin‐releasing hormone neurons in female mice

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Kisspeptin neurons in the rostral hypothalamus are hypothesized to initiate preovulatory gonadotropin‐releasing hormone (GnRH) surges by causing estradiol‐dependent activation of GnRH neuron action potential firing and subsequent GnRH release.
J. Rudolph Starrett, Xi Chen, Devon Krasner, Chrystian D. Phillips, Suzanne M. Moenter   +4 more
wiley   +1 more source

Distinct electrophysiology and dopaminergic modulation of medium spiny neurons across divisions of the tail striatum and the dorsolateral striatum

Experimental Physiology, Volume 111, Issue 10, Page 4827-4851, 1 October 2026.
Abstract The striatum is a brain region within the basal ganglia that plays a crucial role in generating behaviour and mediating perception. The tail striatum (TS) is a poorly understood striatal domain with predominantly sensory functions. Recent evidence supports that abnormal TS dopamine transmission in dopaminergic disease contributes to sensory ...
Bronwyn Riley, Luke E. Hallum, Srdjan M. Vlajkovic, Johanna M. Montgomery, Peter S. Freestone   +4 more
wiley   +1 more source

Tetrodotoxin‐resistant mechanosensitivity and L‐type calcium channel‐mediated spontaneous calcium activity in enteric neurons

Experimental Physiology
Gut motility undergoes a switch from myogenic to neurogenic control in late embryonic development. Here, we report on the electrical events that underlie this transition in the enteric nervous system, using the GCaMP6f reporter in neural crest cell ...
Richard J. Amedzrovi Agbesi, Amira El Merhie, Nick J. Spencer, Tim Hibberd, Nicolas R. Chevalier   +4 more
doaj   +1 more source

Tetrodotoxin: The State-of-the-Art Progress in Characterization, Detection, Biosynthesis, and Transport Enrichment

Marine Drugs
Tetrodotoxin (TTX) is a neurotoxin that binds to sodium channels and blocks sodium conduction. Importantly, TTX has been increasingly detected in edible aquatic organisms.
Xinxin Zhang, Kun Qiao, Ruimin Cui, Min Xu, Shuilin Cai, Qilin Huang, Zhiyu Liu   +6 more
doaj   +1 more source

Acute toxicity of tetrodotoxin (TTX). Should tetrodotoxin be part of the PSP class of toxins?

, 2019
Tetrodotoxin recognized as an emerging risk by international regulators Issues with TTX from pufferfish are well-known throughout history. TTX more recently identified in bivalve molluscs: -- Japan (scallops) -- NZ (pipi) -- UK (mussels and oysters ...
Sarah Finch (15395276)
core  

Toxicon [PDF]

Tetrodotoxin (TTX) is an extremely potent paralytic toxin responsible for yearly illness and death around the world. A clinical measurement is necessary to confirm exposure because symptoms of TTX intoxication cannot be distinguished from other paralytic

core  

Studies on Gene Map of 16S rDNA and Protein Profiling of Tetrodotoxin-Producing Bacteria

, 2015
[[abstract]]Tetrodotoxin (TTX) is a low-molecular weight and non-protein neurotoxin. About the TTX-bearing organisms, according to the results of previous studies, TTX was well known produced by exogenously.
Chen, Hung-Hsuan
core  

1. Toxification of pufferfish and transfer of tetrodotoxin (TTX) among TTX-bearing organisms

NIPPON SUISAN GAKKAISHI, 2022
openaire   +1 more source