Results 131 to 140 of about 17,003 (167)

SERS Study of Tetrodotoxin (TTX) by Using Silver Nanoparticle Arrays

Plasmonics, 2009
The optical properties of tetrodotoxin (TTX), a scarce toxin with anesthetic properties, were studied using nanoparticle arrays-assisted surface-enhanced Raman scattering (SERS). The nanoparticles arrays were fabricated using nanosphere lithography and a metallic lift-off process to control the particle size, shape, and spacing in the arrays.
Deng-Fwu Hwang, Hai-Pang Chiang, Wen-Chi Lin   +2 more
exaly   +2 more sources

First identification of tetrodotoxin (TTX) in the flatworm Stylochoplana sp.; a source of TTX for the sea slug Pleurobranchaea maculata

Toxicon, 2015
High concentrations of the neurotoxin tetrodotoxin (TTX) were detected by liquid chromatography-mass spectrometry (LC-MS) in the Platyhelminthes Stylochoplana sp. from Pilot Bay (Tauranga, New Zealand). This is the first detection of TTX in this genus. Concentrations were monitored from March to November (2013) and found to significantly decrease from ...
David Taylor, Lauren Salvitti, Paul Mcnabb   +2 more
exaly   +3 more sources

Ketamine blockage of both tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels of rat dorsal root ganglion neurons

Brain Research Bulletin, 2000
Ketamine, a general anesthetic, has been reported to block sodium channels. Two types of Na(+) channels, tetrodotoxin (TTX)-sensitive (TTX-s) and TTX-resistant (TTX-r), are expressed in dorsal root ganglion (DRG) neurons. The present study was to investigate the effects of ketamine on both types, particularly on TTX-r channels, using whole-cell patch ...
Z Q Zhao, Zhi-Qi Zhao
exaly   +3 more sources

THE SCENT OF DANGER: TETRODOTOXIN (TTX) AS AN OLFACTORY CUE OF PREDATION RISK

Ecological Monographs, 2006
Larvae of the California newt (Taricha torosa) exhibit striking predator-avoidance behavior, escaping to refuges in response to a chemical cue from cannibalistic adults. In laboratory flow-tank experiments, stream water collected near free-ranging adults induced hiding responses in 100% of the larvae tested.
Lee B Kats
exaly   +2 more sources

LC-MS/MS method for the determination of tetrodotoxin (TTX) on a triple quadruple mass spectrometer

Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 2016
Tetrodotoxin (TTX), often referred to as the 'puffer fish' poison, is a marine toxin and it has been identified as the agent responsible for many food poisoning incidents around the world. It is a neurotoxin that blocks voltage-gated sodium channels, resulting in respiratory paralysis and even death in severe cases.
Ambrose Furey, Mary Lehane
exaly   +3 more sources

Quantitative detection of tetrodotoxin (TTX) by a surface plasmon resonance (SPR) sensor

Sensors and Actuators B: Chemical, 2008
Abstract We report the quantitative antibody-based detection of a low-molecular weight molecule tetrodotoxin (TTX) (∼319 Da) by inhibition assay with a surface plasmon resonance (SPR) sensor. A novel anti-TTX antibody sensing surface was developed by chemically immobilizing TTX on a gold film with a mixed self assembled monolayer (SAM) consisting of ...
Shaoyi Jiang, Sherwood Hall
exaly   +2 more sources

Detection of tetrodotoxin (TTX) from two copepods infecting the grass puffer Takifugu niphobles: TTX attracting the parasites?

Toxicon, 2006
In May 2002, two parasitic copepods, Pseudocaligus fugu and Taeniacanthus sp., were collected from the body surface and gill of the grass puffer Takifugu niphobles, respectively, in Takehara city, Hiroshima Prefecture, faced with Seto Inland Sea located in the western part of Japan.
Susumu Ohtsuka, Shigeto Taniyama, Yasuo Shida   +2 more
exaly   +3 more sources

Evaluation of the genotoxic potential of the natural neurotoxin Tetrodotoxin (TTX) in a battery of in vitro and in vivo genotoxicity assays

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2007
The genotoxic potential of the natural neurotoxin Tetrodotoxin (TTX) was evaluated in a battery of in vitro and in vivo genotoxicity assays. These comprised a bacterial reverse-mutation assay (Ames test), an in vitro human lymphocyte chromosome-aberration assay, an in vivo mouse bone-marrow micronucleus assay and an in vivo rat-liver UDS assay. Maximum
Antonio, Guzmán, Antonio R, Fernández de Henestrosa, Ana-Paz, Marín, Ahn, Ho, Jorge I González, Borroto, Inés, Carasa, Lincoln, Pritchard   +6 more
exaly   +3 more sources

Evidence of accumulation of tetrodotoxin (TTX) in tissues and body parts of ectoparasitic copepods via their feeding on mucus of TTX-bearing pufferfish

Toxicon, 2021
Adults of the ectoparasitic copepod Caligus fugu found on tetrodotoxin (TTX)-bearing pufferfish such as Takifugu alboplumbeus and Takifugu flavipterus are known to accumulate TTX in body tissues and parts other than the ovaries, oviducts, eggs, and cuticles.
Tomohisa Kodama, Koichi Ikeda, Osamu Arakawa, Yusuke Kondo, Manabu Asakawa, Kentaro Kawatsu, Susumu Ohtsuka   +6 more
openaire   +2 more sources

Seafood cross-contamination by tetrodotoxin (TTX): management of an unusual route of exposure

Journal of Consumer Protection and Food Safety, 2023
In this study, liquid chromatography with tandem mass spectroscopy was applied to detect Tetrodotoxin and analogues (TTXs) on pufferfish (Sphoeroides marmoratus) tissues, accidentally found in the stomach of a cuttlefish (Sepia officinalis). The cuttlefish tissues were also analysed.
Tinacci L., Malloggi C., Giusti A., Galli F., Dall'Ara S., Armani A.   +5 more
openaire   +2 more sources