Results 101 to 110 of about 27,116 (203)
Seasonal Changes in the Tetrodotoxin Content of the Flatworm Planocera multitentaculata
Marine Drugs, 2017 Tetrodotoxin (TTX) is a potent neurotoxin that acts specifically on voltage-gated sodium channels on excitable membranes of muscle and nerve tissues. The biosynthetic process for TTX is unclear, although marine bacteria are generally thought to be the ...
Riko Yamada +12 more
doaj +1 more source
Impaired Motor Function in a Zebrafish Stathmin‐2 Knockout Model
Developmental Neurobiology, Volume 86, Issue 4, October 2026.ABSTRACT Stathmin‐2 (STMN2) is a microtubule‐associated protein that plays a role in the stability of microtubules in axons of the nervous system of animals. In this study, we generated a novel zebrafish STMN2 knockout (KO) model. STMN2 is represented by two genes in the zebrafish genome: stmn2a and stmn2b.
Tyler J. N. Gurberg +6 more
wiley +1 more source
Toxins, 2019 A novel polyclonal antibody against tetrodotoxin (TTX) was raised using its haptenic antigen, where 4,9-anhydroTTX was reacted with 1,2-ethanedithiol and this derivative was further reacted with keyhole limpet hemocyanin (KLH).
Shigeru Sato +3 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 19, Page 5832-5853, October 2026.Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama +4 more
wiley +1 more source
Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection
Toxins, 2014 Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated puffer fish which are a culinary delicacy, especially in Japan.
Vaishali Bane +4 more
doaj +1 more source
Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes
Glia, Volume 74, Issue 9, September 2026.Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani +5 more
wiley +1 more source
Toxins, 2017 Tetrodotoxin (TTX) is starting to appear in molluscs from the European waters and is a hazard to seafood consumers. This toxin blocks sodium channels resulting in neuromuscular paralysis and even death. As a part of the risk assessment process leading to
Paula Abal +7 more
doaj +1 more source
Concentrations of Tetrodotoxin (TTX) and Its Analogue 4,9-Anhydro TTX in Different Tissues of the Silver-Cheeked Pufferfish (Lagocephalus sceleratus, Gmelin, 1789) Caught in the South-Eastern Mediterranean Sea, Lebanon. [PDF]
Toxins (Basel), 2022 Hassoun AER +6 more
europepmc +1 more source
, 2018 A) Steps to different voltages (indicated) produced inward currents with at least two kinetically distinct components (2Ca solution, n = 6). The fast component was through voltage-gated Na+ channels as it was blocked by application of 1 μM TTX (n = 6 ...
Alexandra V. Ulyanova (5142920) +1 more
core +1 more source
Journal of Neurochemistry, Volume 170, Issue 9, September 2026.In this article, Hannett and colleagues investigate extracellular vesicles (EVs) secreted by neurons, small membrane‐bound organelles that transmit information among cells. They found that EVs are mainly uptaken by target neurons via a mechanism dependent on the membrane scission protein Dynamin.
Victoria Hannett +5 more
wiley +1 more source