Results 61 to 70 of about 19,032 (194)

Puffer smells tetrodotoxin [PDF]

, 2013
Behavioral observation was conducted to test whether olfaction is functional to detect tetrodotoxin (TTX) in tiger puffer Takifugu rubripes using Y-maze. We placed either agarose carrier or one agarose and one agarose containing TTX (200 MU) at each head
Okita, Kogen, Arakawa, Osamu, Sakakura, Yoshitaka, Takatani, Tomohiro, Yamazaki, Hideki, Yamane, Hikaru, Sakiyama, Kazutaka, Niina, Shinya   +7 more
core   +1 more source

Tetrodotoxin, fungal pathogen infection, and bacterial microbiome associations are variable in the skin microecosystems of two Taricha newt species

Frontiers in Amphibian and Reptile Science
A diverse metabolome exists on amphibian skin that mediates interactions between hosts and skin microbiomes. Tetrodotoxin is one such metabolite that occurs across a variety of taxa, and is particularly well studied in newts of the genus Taricha that are
Talon Jost, Talon Jost, Alysha Henderson, Brandon LaBumbard, Krisztian Magori, Amber Stokes, Danica Bergin, Autumn Holley, Autumn Holley, Molly Bletz, Molly Bletz, Obed Hernández-Gómez, Gary Bucciarelli, Douglas C. Woodhams, Jonah Piovia-Scott, Jenifer B. Walke   +15 more
doaj   +1 more source

Memantine prevents acute stress‐induced memory deficits by reversing sex‐dependent pathophysiological glutamatergic alterations in the dorsal hippocampus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The neural mechanisms underlying effects of acute stress on memory are poorly understood. We demonstrated previously that acute stress produces identical spatial memory deficits in male and female mice but through distinct molecular mechanisms, with females exhibiting up‐regulation of N‐methyl‐D‐aspartate (NMDA) receptor
Sebastiano A. Torrisi, Lidia Diolosà, Giuseppe Aceto, Claudia Marchetti, Federica Geraci, Konstantinos Partsinevelos, Silvia Rizzo, Margherita Grasso, Filippo Caraci, Francesco Bellia, Giovanni Li Volti, Angela Maria Amorini, Marcello D′Ascenzo, Gian Marco Leggio   +13 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

An improved competitive inhibition enzymatic immunoassay method for tetrodotoxin quantification

Biological Procedures Online, 2012
Quantifying tetrodotoxin (TTX) has been a challenge in both ecological and medical research due to the cost, time and training required of most quantification techniques.
Stokes Amber N, Williams Becky L, French Susannah S   +2 more
doaj   +1 more source

Integration of cortical inputs in the lateral hypothalamus is dominated by the medial prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend The lateral hypothalamus (LH) is a critical controller of innate behaviours such as feeding. It is anatomically connected to specific cortical areas. We mapped these areas using a combination of retrograde tracing and anterograde optogenetic circuit mapping.
Lotte J. A. M. Razenberg, Pieter Nicolaas de Greef, Huibert D. Mansvelder, Mahesh Miikael Karnani   +3 more
wiley   +1 more source

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

The Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang, Pabitra Hriday Patra, Jinquan Yang   +2 more
wiley   +1 more source

Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current

Marine Drugs, 2011
Evolutionary origin and physiological significance of the tetrodotoxin (TTX) resistance of the vertebrate cardiac Na+ current (INa) is still unresolved.
Jaakko Haverinen, Minna Hassinen, Matti Vornanen   +2 more
doaj   +1 more source

Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors

Glia, Volume 74, Issue 8, August 2026.
In early brain development, neuronal activity reduces OPC differentiation. Decreased neuronal activity changes oligodendrocyte gene expression, including upregulating glutamate receptor genes. AMPA signaling regulates the final stages of OPC differentiation.
Tessa E. Allen, Graham Peet, Luis E. Gomez Wulschner, Won Chan Oh, Wendy B. Macklin   +4 more
wiley   +1 more source

Spatial variability and depuration of tetrodotoxin in the bivalve Paphies australis from New Zealand

Toxicon: X, 2019
Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications globally. Despite its potency and widespread occurrence in taxonomically diverse species, the primary source of TTX remains uncertain.
Laura Biessy, Kirsty F. Smith, D. Tim Harwood, Michael J. Boundy, Ian Hawes, Susanna A. Wood   +5 more
doaj   +1 more source