Results 191 to 200 of about 14,813 (212)

The Genome of Transmissible Gastroenteritis Virus (TGEV)

1984
Lysis of isolated TGE virions with sodium dodecyl sulphate (SDS) at room temperature followed by electrophoresis, yields predominantly a single band of RNA running at about molecular weight 6.8 × 106. Heating the SDS lysate at 80°C for 15 min prior to electrophoresis results in a cluster of bands of between 0.2–6.8 × 106.
Lynne Bountiff, David J. Garwes, Geoffrey C. Millson, G. David Baird   +3 more
openaire   +1 more source

p53 mediated IFN-β signaling to affect viral replication upon TGEV infection

Veterinary Microbiology, 2018
TGEV can induce IFN-β production, which in turn plays a vital role in host antiviral immune responses. Our previous studies showed that TGEV infection activated p53 signaling to induce host cell apoptosis, which might influence virus replication. However, whether there be an interaction between p53 and IFN-β signaling in the process of TGEV infection ...
Li Ding, Meiling Hong
exaly   +3 more sources

Competition ELISA, using monoclonal antibodies to the transmissible gastroenteritis virus (TGEV) S protein, for serologic differentiation of pigs infected with TGEV or porcine respiratory coronavirus

American Journal of Veterinary Research, 1993
SUMMARY Monoclonal antibodies (MAB) to subsite A (25C9) and subsite D (44C11) of the S protein of transmissible gastroenteritis virus (tgev) were used in a blocking elisa on fixed tgev-infected swine testis cells to differentiate sera from pigs experimentally inoculated with either tgev or porcine respiratory coronavirus (prcv).
R A, Simkins, P A, Weilnau, J, Van Cott, T A, Brim, L J, Saif   +4 more
openaire   +2 more sources

Overexpression of TGEV Cell Receptor Impairs the Production of Virus Particles

1995
The porcine aminopeptidase-N (pAPN) is the cellular receptor for the transmissible gastroenteritis virus (TGEV) due to the specific binding of the spike protein S to APN. In the present study, we performed both biological and biochemical experiments to analyze how the level of expression of a virus receptor can influence the viral protein biosynthesis ...
Delmas, Bernard, Kut, Emmanuel, Gelfi, Jacqueline, Laude, Hubert   +3 more
openaire   +3 more sources

TGEV NSP1 enhances viral replication through antagonizing stress granule formation

Veterinary Microbiology
Stress granules (SGs) are membrane-less organelles that form in response to adverse external stimuli. Upon viral invasion, SGs formation can serve as a cellular defence mechanism against infection. Transmissible gastroenteritis virus (TGEV), an α-coronavirus with a large positive-sense single-stranded RNA genome, causes diarrhoea, vomiting, dehydration,
Guangliang Liu
exaly   +3 more sources

Antibody Response in Swine to Individual Transmissible Gastroenteritis Virus (TGEV) Proteins

1987
Transmissible gastroenteritis virus (TGEV) is a coronavirus that produces a life-threatening diarrhea in neonatal pigs. Whereas sows infected with virulent virus produce protective colostral antibody, sows vaccinated with attenuated virus are significantly less effective in passively protecting baby pigs.
R, Wesley, R, Woods, P, Kapke
openaire   +2 more sources

The Use of PCR Genome Mapping for the Characterisation of TGEV Strains

1994
Previous studies on different transmissible gastroenteritis virus (TGEV) strains, including porcine respiratory coronavirus (PRCV), have identified regions within the genome that are polymorphic as regards insertions and deletions. For example the 672 base deletion within the S gene and multiple deletions 5', within and 3' of the ORF-3a gene were ...
Britton, P., Kottier, S., Chen, C.M., Pocock, D.H., Salmon, Henri, Aynaud, J.M.   +5 more
openaire   +3 more sources

Field Validation of a Commercial Blocking ELISA to Differentiate Antibody to Transmissible Gastroenteritis Virus (TGEV) and Porcine Respiratory Coronavirus and to Identify TGEV-Infected Swine Herds

Journal of Veterinary Diagnostic Investigation, 2002
A commercially available blocking ELISA was analyzed for its ability to identify antibodies to porcine coronaviruses (transmissible gastroenteritis virus [TGEV] or porcine respiratory coronavirus [PRCV]), to differentiate antibodies to TGEV and PRCV, and to identify TGEV-infected herds.
Susy, Carman, Gaylan, Josephson, Beverly, McEwen, Grant, Maxie, Mioara, Antochi, Ken, Eernisse, Gopi, Nayar, Pat, Halbur, Gene, Erickson, Ernst, Nilsson   +9 more
openaire   +2 more sources

Swine Enteric Coronaviruses (PEDV, TGEV, and PDCoV) Induce Divergent Interferon-Stimulated Gene Responses and Antigen Presentation in Porcine Intestinal Enteroids

Frontiers in Immunology, 2022
Xiang Liu, Pinghuang Liu
exaly  

Persistence Infection of TGEV Promotes Enterococcus faecalis Infection on IPEC-J2 Cells

International Journal of Molecular Sciences, 2023
Jiajun Dong
exaly