Results 151 to 160 of about 138,672 (332)
Human Resting CD4+ T Cells Are Constitutively Inhibited by TGFβ under Steady-State Conditions [PDF]
, 2007 Sabine Claßen +10 more
openalex +1 more source
, 2010 O titânio é bastante utilizado para confeccionar implantes dentários e ortopédicos devido as suas propriedades físicas e biocompatibilidade. Modificações na superfície e rugosidade do titânio podem ser realizadas a fim de melhorar o reparo ósseo ao redor do implante.
Moura, Cláudia C.L. +3 more
openaire +1 more source
Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Advanced Science, EarlyView.Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Advanced Science, EarlyView.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source
A microRNA signature of response to erlotinib is descriptive of TGFβ behaviour in NSCLC
Scientific Reports, 2017 Our previous work identified a 13-gene miRNA signature predictive of response to the epidermal growth factor receptor (EGFR) inhibitor, erlotinib, in Non-Small Cell Lung Cancer cell lines.
Madeline Krentz Gober +3 more
doaj +1 more source
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy. [PDF]
, 2019 Many potentially therapeutic molecules have been identified for treating Duchenne muscular dystrophy. However, targeting those molecules only to sites of active pathology is an obstacle to their clinical use.
Bertoni, Carmen +6 more
core
Advanced Science, EarlyView.Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu +11 more
wiley +1 more source
Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model [PDF]
, 2021 Tereza Andreou +9 more
openalex +1 more source