TGFβ limits proximal CD8+ TCR signaling via PTPN22 following strong and moderate agonism. [PDF]
Gunderson AJ +9 more
europepmc +1 more source
Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni +7 more
wiley +1 more source
Unravelling the therapeutic potential of dual TGFβ-1 and CXCR4 inhibition in breast cancer using computational strategies. [PDF]
Haq BU +10 more
europepmc +1 more source
Oral wound healing in the elderly: Mechanisms, challenges, and innovations
Abstract Objective This narrative synthesizes current knowledge on the biological mechanisms, clinical challenges, and regenerative innovations for optimizing intraoral wound healing in the elderly. Methods Narrative review of preclinical and clinical studies addressing age‐related changes in the four canonical wound‐healing phases (hemostasis ...
Ann M. Decker +7 more
wiley +1 more source
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis. [PDF]
Bhamidipati K +32 more
europepmc +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Left-Right Determination Factor 2 (LEFTY2) Is an Aqueous Humor Biomarker for Exfoliation Glaucoma. [PDF]
Smith AJO +11 more
europepmc +1 more source
Abstract Objective The purpose of this case series was to describe the effect of autologous PRF membrane for corneal reconstruction surgery in dogs. PRF membranes made from two healthy dogs unrelated to the current case series were used for PRF histologic analyses. Animals Seven dogs with complicated corneal ulcerations. Procedure A complete ophthalmic
Louise Baadsgaard Bruun +6 more
wiley +1 more source
Filamin A phosphorylation at S2152: a molecular switch fueling cancer and neurodegeneration. [PDF]
Burns LH, Romero A.
europepmc +1 more source

