Results 161 to 170 of about 431,292 (339)

Retraction notice to “Amelioration of UV radiation-induced photoaging by a combinational sunscreen formulation via aversion of oxidative collagen degradation and promotion of TGF-β-Smad-mediated collagen production” [European Journal of Pharmaceutical Sciences 127 (2019) 261-275]

, 2022
Nilutpal Sharma Bora, Bhaskar Mazumder, Santa Mandal, Pompy Patowary, Danswrang Goyary, Pronobesh Chattopadhyay, Sanjai K. Dwivedi   +6 more
openalex   +1 more source

Additional file 1: of FOXP3 Is a HCC suppressor gene and Acts through regulating the TGF-β/Smad2/3 signaling pathway

, 2017
Supplementary Methods. (DOC 37 kb)
Shi, Jie-Yi, Ma, Li-Jie, Zhang, Ji-Wei, Duan, Meng, Ding, Zhen-Bin, Liu-Xiao Yang, Cao, Ya, Zhou, Jian, Fan, Jia, Xiaoming Zhang, Zhao, Ying-Jun, Wang, Xiao-Ying, Gao, Qiang   +12 more
openaire   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway [PDF]

, 2019
Shuangqing Li, Chao Tu, Lu Wan, Ruiqi Chen, Zhixi Duan, Xiaolei Ren, Zhihong Li   +6 more
openalex   +1 more source

MOESM1 of miR-335-5p inhibits TGF-β1-induced epithelialâ mesenchymal transition in non-small cell lung cancer via ROCK1

, 2019
Additional file 1: Table S1. The sequences of primers involved in our study.
Wenwen Du, Haicheng Tang, Lei, Zhe, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Huang, Jian-An   +6 more
openaire   +1 more source

IL‐2 Free Expansion of T Cells with Immunofilaments

Advanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck, Lea Weiss, René Classens, Carl G. Figdor, Roel Hammink   +4 more
wiley   +1 more source

OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis [PDF]

, 2016
关于TGF-β信号在诱导上皮-间质转化（EMT）过程中的作用的研究在多种肿瘤中已经取得了很大的进展，然而，在乳腺肿瘤转移的过程中，TGF-β信号对EMT的调控机制尚未完全探明。在本研究中，我们证明了OVOL2，一种锌指蛋白转录因子，能抑制小鼠肿瘤细胞、人乳腺肿瘤细胞中的TGF-β信号诱导的EMT。从Oncomine数据库中获得的数据表明，OVOL2的表达与乳腺癌的进展之间存在着很强的负相关关系。此外，我们的实验表明，OVOL2在多个水平上抑制TGF-β信号，包括抑制Smad4mRNA的表达 ...
吴容思
core  

MOESM3 of miR-335-5p inhibits TGF-β1-induced epithelialâ mesenchymal transition in non-small cell lung cancer via ROCK1

, 2019
Additional file 3: Table S2. Clinicopathological features of NSCLC tissues from 30 patients with non-lymph node metastasis and 30 patients with lymph node metastasi.
Wenwen Du, Haicheng Tang, Lei, Zhe, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Huang, Jian-An   +6 more
openaire   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Recent advances in therapeutic use of transforming growth factor-beta inhibitors in cancer and fibrosis

Frontiers in Oncology
Transforming growth factor-beta (TGF-β) has long been known to be associated with early embryonic development and organogenesis, immune supervision, and tissue repair and homeostasis in adults.
Hanhui Jing, Yan Gao, Linyuan Jing, Hanyu Yang, Shanglong Liu   +4 more
doaj   +1 more source