Results 201 to 210 of about 320,405 (317)

Image 1_Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration.tif

Enxu Liu (21190403), Yu Sun (18463), Lei Yang (102719), Haobo Jiang (47337), Fei Sun (102854), Long Chen (315739), Jiahao Duan (10014005), Shaofeng Yang (1297038)   +7 more
openalex   +1 more source

Directed Blocking of TGF-β Receptor I Binding Site Using Tailored Peptide Segments to Inhibit its Signaling Pathway.

, 2020
Sepideh Sepehri, Shahriar Arab, Mehrdad Behmanesh, Reza H. Sajedi   +3 more
openalex   +2 more sources

Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung

Advanced Science, EarlyView.
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu, Saiya Li, Guodong Wu, Shuangjian Li, Long Shuang Huang, Xiaoyang Li, Yiguo Zhao, Wei Lu, Cuixia Sun, Qin Cao, Yapeng Fang, Yiping Cao   +11 more
wiley   +1 more source

Reactive Nitrogen-Dominant Plasma Accelerates Diabetic Wound Healing Through Regulated Angiogenesis and TGF-β Normalisation. [PDF]

Int Wound J
Cheng YP, Chou-Huang TY, Lee CC, Chen HL, Cheng KY, Wu MC, Huang SS, Guo JW, Wu JS.   +8 more
europepmc   +1 more source

Truncated forms of RUNX3 Unlike Full Length Protein Alter Cell Proliferation in a TGF-β Context Dependent Manner.

, 2017
Narges Rahmanian, Parastoo Tarighi, Mehdi Gharghabi, Maryam Torshabi, Ghorban Ali Tarfiei, Taiebeh Mohammadi Farsani, Seyed Nasser Ostad, Mohammad Hossein Ghahremani   +7 more
openalex   +1 more source

Effects of sulpiride on mRNA and protein expression of factors in the YAP-TGF-β-Smad signaling pathway in ARPE-19 cells.

Jing Fan (149601), Qiujin Zhang (472724), Liu Zheng (1880860), Binbin Yang (2259313), He Jin (12261804), Tingyu Meng (22560141), Zhixiang Ding (15349443)   +6 more
openalex   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Comprehensive analysis of the TGF-β signaling pathway: molecular mechanisms, disease drivers, and frontiers in clinical translation. [PDF]

Front Immunol
Zhang Y, Tang H, Zhou Z, Liao J, Zhou X, Chu X, Shao M, Zhang C, Jiang L.   +8 more
europepmc   +1 more source

TGF-β Signaling Pathways in the Development of Diabetic Retinopathy [PDF]

Andrew Callan, Sonal Jha, Laura B. Valdez, Lois Baldado, Andrew Tsin   +4 more
openalex   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source