Results 161 to 170 of about 1,017,685 (306)

Chronic exposure of mice to phthalates enhances TGF beta signaling and promotes uterine fibrosis. [PDF]

Reprod Toxicol, 2023
Shukla R, Arshee MR, Laws MJ, Flaws JA, Bagchi MK, Wagoner Johnson AJ, Bagchi IC.   +6 more
europepmc   +1 more source

AI‐Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis

Advanced Science, EarlyView.
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han, Yao Zhao, Chengbo Yang, Miao Niu, Jun Dai, Quanxin Ning, Kai Xiao, Jinzheng Liang, Wensheng Zhang, Liang Wang, Dan Shao, Dongsong Li   +11 more
wiley   +1 more source

Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity. [PDF]

Cell Death Discov
Chua OWH, Duan L, Bothe SH, Evsyukov V, Moebius C, Bickle M, Höglinger GU, Höllerhage M.   +7 more
europepmc   +1 more source

Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma. [PDF]

Redox Biol, 2023
Espinosa-Sotelo R, Fusté NP, Peñuelas-Haro I, Alay A, Pons G, Almodóvar X, Albaladejo J, Sánchez-Vera I, Bonilla-Amadeo R, Dituri F, Serino G, Ramos E, Serrano T, Calvo M, Martínez-Chantar ML, Giannelli G, Bertran E, Fabregat I.   +17 more
europepmc   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Editorial: The role of TGF-beta superfamily members in immune homeostasis and disease. [PDF]

Front Immunol
Nieuwenhuizen NE, Eleftherianos I, Kraj PJ, Semitekolou M.   +3 more
europepmc   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Distribution of transforming growth factor-beta isoforms TGF-beta 1, TGF-beta 2 and TGF-beta 3 and vascular endothelial growth factor in vulvar lichen sclerosus.

, 2001
OBJECTIVE: To study the distribution of transforming growth factor beta (TGF-beta) isoforms TGF-beta 1, TGF-beta 2 and TGF-beta 3 and vascular endothelial growth factor (VEGF) in vulvar lichen sclerosus.
Dean, D, Farrell, AM, Charnock, M, Wojnarowska, F   +3 more
core  

Targeting noncanonical TGF-beta signaling: inhibition effects on the human keloid fibroblast transcriptome. [PDF]

Itch (Phila)
Morningstar J, Sivadas A, Romeo M, Vaena S, Valdebran M, Kwatra SG, Norris RA, Beck TC.   +7 more
europepmc   +1 more source

TGF Beta as a Prognostic Biomarker of COVID-19 Severity in Patients with NAFLD-A Prospective Case-Control Study. [PDF]

Microorganisms, 2023
Susak F, Vrsaljko N, Vince A, Papic N.
europepmc   +1 more source