Results 251 to 260 of about 1,017,685 (306)
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[Rinsho ketsueki] The Japanese journal of clinical hematology, 1994
In the present paper, we investigated the pathophysiological implication of TGF-beta from megakaryocytes or megakaryoblasts in the development of myelofibrosis. In the bone marrow of myelofibrosis, proliferation of megakaryocytes is often noticed.
K, Kogawa +4 more
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In the present paper, we investigated the pathophysiological implication of TGF-beta from megakaryocytes or megakaryoblasts in the development of myelofibrosis. In the bone marrow of myelofibrosis, proliferation of megakaryocytes is often noticed.
K, Kogawa +4 more
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TGF beta −1, −2 and −3 in the modulation of fibrosis in the cornea and other organs
Experimental Eye Research, 2021Steven E. Wilson
exaly
General pharmacology, 1998
Vitamin D3 and transforming growth factor-beta (TGF-beta) are molecules from unrelated families that share identical actions on cell growth and differentiation. The active metabolite of vitamin D3, calcitriol (1alpha,25-dihydroxyvitamin D3), induces an inhibitory effect on the growth of various cell types, and the expression of different markers of ...
C, Heberden +3 more
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Vitamin D3 and transforming growth factor-beta (TGF-beta) are molecules from unrelated families that share identical actions on cell growth and differentiation. The active metabolite of vitamin D3, calcitriol (1alpha,25-dihydroxyvitamin D3), induces an inhibitory effect on the growth of various cell types, and the expression of different markers of ...
C, Heberden +3 more
openaire +1 more source
Cytokine & growth factor reviews, 2009
TGF-beta signaling regulates tumorigenesis and in human cancer its signaling pathways are often modified during tumor progression. Prior to initiation and early during progression TGF-beta acts upon the epithelium as a tumor suppressor, however at later stages it is often a tumor promoter.
Brian, Bierie, Harold L, Moses
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TGF-beta signaling regulates tumorigenesis and in human cancer its signaling pathways are often modified during tumor progression. Prior to initiation and early during progression TGF-beta acts upon the epithelium as a tumor suppressor, however at later stages it is often a tumor promoter.
Brian, Bierie, Harold L, Moses
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Ciba Foundation symposium, 1991
TGF-beta binds specifically and with high affinity to all cell types with few exceptions. The binding parameters vary because the dissociation constants range from 1 pM to 60 pM. There may be as few as 200 or as many as 100,000 receptors per cell, depending on the cell type. Several cell surface proteins that specifically bind TGF-beta 1 and TGF-beta 2
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TGF-beta binds specifically and with high affinity to all cell types with few exceptions. The binding parameters vary because the dissociation constants range from 1 pM to 60 pM. There may be as few as 200 or as many as 100,000 receptors per cell, depending on the cell type. Several cell surface proteins that specifically bind TGF-beta 1 and TGF-beta 2
openaire +1 more source
Immunity, 2010
Is transforming growth factor-beta (TGF-beta) required for induction of the transcription factor Foxp3 in developing thymocytes? Ouyang et al. (2010) demonstrate that TGF-beta in the thymus prevents deletion of Foxp3(+) regulatory T cells.
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Is transforming growth factor-beta (TGF-beta) required for induction of the transcription factor Foxp3 in developing thymocytes? Ouyang et al. (2010) demonstrate that TGF-beta in the thymus prevents deletion of Foxp3(+) regulatory T cells.
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Microbes and infection, 2000
The relationships between transforming growth factor-beta (TGF-beta) and cancer are varied and complex. The paradigm that is emerging from the experimental evidence accumulated over the past decade or so is that TGF-beta can play two different and opposite roles with respect to the process of malignant progression. During early stages of carcinogenesis,
openaire +1 more source
The relationships between transforming growth factor-beta (TGF-beta) and cancer are varied and complex. The paradigm that is emerging from the experimental evidence accumulated over the past decade or so is that TGF-beta can play two different and opposite roles with respect to the process of malignant progression. During early stages of carcinogenesis,
openaire +1 more source