Results 291 to 300 of about 199,388 (309)
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Aire functions in negative selection of self-reactive TCR during lymphocyte development through activation of tissue-restricted antigen, or TRA. This occurs specifically in the mTEC cells of the thymus, where Aire expression is generally restricted to (1) Tolerogenic signaling through Aire in the periphery was previously suggested (2).
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IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Nature, 2007Thomas Korn, Estelle Bettelli, Wenda Gao
exaly
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
Nature, 2013Markus Kleinewietfeld +2 more
exaly
Induction and molecular signature of pathogenic TH17 cells
Nature Immunology, 2012Youjin Lee, Amit Awasthi, Nir Yosef
exaly
Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
Nature, 2013Chuan Wu, Nir Yosef, Aviv Regev
exaly
IL-21 and TGF-β are required for differentiation of human TH17 cells
Nature, 2008Estelle Bettelli
exaly

