Results 151 to 160 of about 306,117 (176)

Activation of Peripheral Th17 Lymphocytes in Patients with Asthma

Immunological Investigations, 2009
A recently identified interleukin (IL)-17-producing T-helper (Th) lymphocyte subset, which comprises Th17 cells producing hallmark cytokines IL-17A, IL-17F and IL-22, is involved in chronic inflammatory diseases. Elevated gene and protein expressions of IL-17 are manifested in allergic asthma.
C W K Lam, D S C Hui, I H S Chan
exaly   +3 more sources

Autoimmune thyroid diseases and Th17/Treg lymphocytes

Life Sciences, 2018
Years of researches have demonstrated that the imbalance of Th17 and Tregs contribute to the thyroid autoimmunity and the severity of autoimmune thyroid disease (AITD). The underlying mechanism comprises inherent genetic predisposition, abnormality of Th17 and Treg related biological molecules, and gut microbiota disorder.
Shiying Shao, Xuefeng Yu
exaly   +3 more sources

Th17 and Th1 Lymphocytes Are Correlated with Chronic Periodontitis

Immunological Investigations, 2016
T cells are involved in the homeostasis of periodontal tissues and mediate bone loss in periodontitis, but the involvement of T-helper cells in chronic periodontitis (CP) in a Chinese population is still unclear. This study aimed to assess the distribution of peripheral and local T helper (Th17) and Th1 in CP.
Xiao-Tao, Chen, Li-Li, Chen, Jing-Yi, Tan, Dan-Hui, Shi, Ting, Ke, Li-Hong, Lei   +5 more
openaire   +2 more sources

Factors of Th17 and Treg Lymphocyte Differentiation in Pulmonary Tuberculosis

Bulletin of Experimental Biology and Medicine, 2015
In patients with infiltrative pulmonary tuberculosis, the increase in IL-6 secretion, the decrease in TGFβ production (in case of drug resistance of the causative agent), and unchanged level of IL-1β secretion by mononuclear leukocytes in vitro were associated with increased number of CD4(+)CD161(+)IL-17A(+) Th17 lymphocytes in the peripheral blood. In
T E, Kononova, O I, Urazova, V V, Novitskii, Yu V, Kolobovnikova, E G, Churina, P A, Zakharova   +5 more
openaire   +2 more sources

The role of Th17 lymphocytes in the autoimmune and chronic inflammatory diseases

Internal and Emergency Medicine, 2011
The emerging role of interleukin-17 as a hallmark proinflammatory cytokine of the adaptive immune system produced by a new T helper cell subset termed "Th17" has received considerable attention. In this review we will focus on recent information regarding IL-17 and its relevance in autoimmune and chronic inflammatory diseases.
MURDACA, GIUSEPPE, Colombo B.M., PUPPO, FRANCESCO   +2 more
openaire   +2 more sources

Tregs and Th17 lymphocytes in human DYRK1A haploinsufficiency

Immunology Letters, 2019
The DYRK1A gene encodes for a dual-specific tyrosine phosphorylation-regulated kinase 1A involved in different cellular processes such as cell differentiation, proliferation and survival. This tyrosine kinase plays a key role in brain growth and function.
Valencic E., Piscianz E., Sirchia F., Tommasini A., Faletra F., Todaro F., Spinelli A. M., Badolato R.   +7 more
openaire   +4 more sources

The role of Th17 lymphocytes in drug-resistant epilepsy

The Journal of Immunology, 2019
Abstract Epilepsy is a chronic neuronal disorder affecting ~65 millions people throughout the world. 1/3 of patients suffer from drug-resistant epilepsy (DRE). Objective to assess the relationship between different Th17 markers and the clinical course of epilepsy to uncover new ...
Oumarou Ouédraogo, Hélène Jamann, Audrey Daigneault, Marie-Laure Clenet, Boaz Lahav, A Bérubé, Patrick Cossette, Mark Keezer, Dang Khoa Nguyen, Catherine Larochelle   +9 more
openaire   +1 more source

Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission

Arthritis & Rheumatism, 2008
Abstract Objective The recently characterized interleukin‐17 (IL‐17)–producing T helper cell lineage (Th17), rather than the Th1 lineage, is involved in several autoimmune diseases. The possible role of Th17 cells in Wegener's granulomatosis (WG) has not yet been elucidated.
Abdulahad, Wayel Habib, Stegeman, Coen, Limburg, Piet, Kallenberg, Cees   +3 more
openaire   +2 more sources

Th17 and Treg lymphocytes in obesity and Type 2 diabetic patients

Clinical Immunology, 2018
Assumption that the pathogenesis of obesity-associated type 2 diabetes (T2DM) encompasses inflammation and autoimmune aspects is increasingly recognized. In the state of obesity and T2DM, the imbalance of T helper 17 (Th17) cells and regulatory T (Treg) cells are observed.
Mei, Wang, Fuqiong, Chen, Jingli, Wang, Zhixuan, Zeng, Qin, Yang, Shiying, Shao   +5 more
openaire   +2 more sources

[The latest TH17 lymphocyte in the family of T CD4+ lymphocytes].

Pathologie-biologie, 2011
In recent years the T CD4+ lymphocyte family has grown. In the initial two components TH1 and TH2 lymphocytes were added the TH17 lymphocyte and T cell regulator (Treg). Under the influence of transforming growth factor β, interleukin 6 (IL6), IL21 and IL23, the naive lymphocyte T CD4+ differentiates in TH17.
M, Essakalli, C, Brick, N, Bennani, N, Benseffaj, S, Ouadghiri, O, Atouf   +5 more
openaire   +1 more source