Results 141 to 150 of about 79,137 (281)

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Escherichia coli aggravates inflammatory response in mice oral mucositis through regulating Th17/Treg imbalance

Frontiers in Cellular and Infection Microbiology
IntroductionMicrobial dysbiosis links to mucosal immune dysregulation, but the specific bacterial contributions to oral mucosal inflammation remain unclear. Escherichia coli (E.
Jia Liu, Jia Liu, Jia Liu, Wenhui Xia, Wenhui Xia, Wenhui Xia, Wenhui Xia, Juehua Cheng, Juehua Cheng, Juehua Cheng, Yanlin Geng, Yanlin Geng, Yanlin Geng, Weiping Li, Weiping Li, Weiping Li, Yuan Fan, Yuan Fan, Yuan Fan   +18 more
doaj   +1 more source

Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis.

, 2012
International audienceOBJECTIVE: Giant cell arteritis (GCA) is the most frequently occurring vasculitis in elderly individuals, and its pathogenesis is not fully understood.
Maillefert, Jean-Francis, Martin, Laurent, Bonnotte, Bernard, Bateman, Andrew, Trad, Malika, Vinit, Julien, Lakomy, Daniela, Mouthon, Luc, Ornetti, Paul, Aho-Glele, Serge, Janikashvili, Nona, Olsson, Nils Olivier, Berthier, Sabine, Larmonier, Nicolas, Guillevin, Loïc, Lorcerie, Bernard, Audia, Sylvain, Saas, Philippe, Samson, Maxime, Manckoundia, Patrick, Fraszczak, Jennifer, Leguy, Vanessa, Ciudad, Marion, Besancenot, Jean-François   +23 more
core   +1 more source

Current Progress in Differentiating Crohn's Disease From Intestinal Tuberculosis

iLABMED, EarlyView.
Currently, there are various methods from different fields used to differentiate Crohn's disease from intestinal tuberculosis (ITB). Endoscopic findings are an important cornerstone. They can be used individually or in combination (models) to demonstrate excellent discriminative ability.
Chuyao Zhang, Xiaoyin Zhang
wiley   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Analysis of murine lamina propria TH17 cells

, 2015
<p>IL-17-expressing CD4+ cells (TH17 cells) constitute a considerable proportion of lymphocytes in the intestinal lamina propria (LP), even in healthy mice kept under specific pathogen free conditions.
sprotocols
core   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis. [PDF]

Proc Natl Acad Sci U S A, 2020
Platt MP, Bolding KA, Wayne CR, Chaudhry S, Cutforth T, Franks KM, Agalliu D.   +6 more
europepmc   +1 more source

Rôles des cellules myéloïdes suppressives et des lymphocytes Th17 dans le cancer

, 2012
Le système immunitaire joue un double rôle dans le cancer: il peut non seulement supprimer la croissance tumorale en détruisant les cellules cancéreuses, mais aussi promouvoir la progression de la tumeur en sélectionnant les cellules tumorales ou en ...
GHIRINGHELLI, François, CHALMIN, Fanny
core