Results 121 to 130 of about 79,137 (281)
Chronic obstructive pulmonary disease (COPD) is a global public health problem. Studies in immunological features and their correlations with clinical course of COPD are of importance.
E. P. Kalinina +5 more
doaj +1 more source
Th17 and Treg lymphocytes as cellular biomarkers of disease activity in Granulomatosis with Polyangiitis [PDF]
Granulomatosis with Polyangiitis (GPA) (formerly known as Wegener's granulomatosis) is a vasculitis of unknown etiology affecting predominantly small‐ to medium‐sized vessels, usually involving the upper and lower respiratory tract and kidneys. Anti‐neutrophil cytoplasmic autoantibodies are probably the initial cause of the inflammatory process that ...
openaire +3 more sources
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T‐cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova +6 more
wiley +1 more source
L’exposition à la fumée de cigarette induit la sénescence des lymphocytes T CD4+ Th17 humains
Smoking worsens chronic inflammatory diseases (COPD, Crohn disease, rheumatoid arthritis, psoriasis) associated with inflammatory CD4+ IL-17 secreting lymphocytes (Th17).
Kerbrat, Stéphane
core +1 more source
Interleukin-17 and Th17 Lymphocytes Directly Impair Motoneuron Survival of Wildtype and FUS-ALS Mutant Human iPSCs. [PDF]
Jin M +5 more
europepmc +1 more source
Estrogen treatment exerts a protective effect on experimental autoimmune encephalomyelitis (EAE) and is under clinical trial for multiple sclerosis therapy.
Therese Périnat +18 more
core +1 more source
The Th17 pathway in Cystic Fibrosis lung disease [PDF]
In contrast to the neutrophilic inflammation found in the airway lumen, lymphocytes predominate in the airway wall of Cystic fibrosis (CF) patients.
Tan, Hui-leng
core +1 more source
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Change of Th17 lymphocytes and Treg/Th17 in Typical and Atypical Optic Neuritis (.pdf)
Typical and atypical optic neuritis (ON) are two types of autoimmune inflammatory diseases of the optic nerve that causes acute vision loss, and which are difficult to distinguish in their early stages.
Xiaojun Zhang; Hengri Cong; Hanqiu Jiang; Jingting Peng; Shilei Cui; Lijuan Liu
core

