Results 121 to 130 of about 79,137 (281)

CLINICAL AND IMMUNOLOGICAL COMPARISONS IN Th- DEPENDENT IMMUNE RESPONSE MECHANISMS AMONG PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

open access: yesМедицинская иммунология, 2018
Chronic obstructive pulmonary disease (COPD) is a global public health problem. Studies in immunological features and their correlations with clinical course of COPD are of importance.
E. P. Kalinina   +5 more
doaj   +1 more source

Th17 and Treg lymphocytes as cellular biomarkers of disease activity in Granulomatosis with Polyangiitis [PDF]

open access: yesEuropean Journal of Immunology, 2017
Granulomatosis with Polyangiitis (GPA) (formerly known as Wegener's granulomatosis) is a vasculitis of unknown etiology affecting predominantly small‐ to medium‐sized vessels, usually involving the upper and lower respiratory tract and kidneys. Anti‐neutrophil cytoplasmic autoantibodies are probably the initial cause of the inflammatory process that ...
openaire   +3 more sources

Homocitrullinated Peptides Drive Pro‐Inflammatory T‐Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T‐cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova   +6 more
wiley   +1 more source

L’exposition à la fumée de cigarette induit la sénescence des lymphocytes T CD4+ Th17 humains

open access: yes, 2016
Smoking worsens chronic inflammatory diseases (COPD, Crohn disease, rheumatoid arthritis, psoriasis) associated with inflammatory CD4+ IL-17 secreting lymphocytes (Th17).
Kerbrat, Stéphane
core   +1 more source

Estrogen Receptor α Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection against Experimental Autoimmune Encephalomyelitis

open access: yes, 2011
Estrogen treatment exerts a protective effect on experimental autoimmune encephalomyelitis (EAE) and is under clinical trial for multiple sclerosis therapy.
Therese Périnat   +18 more
core   +1 more source

The Th17 pathway in Cystic Fibrosis lung disease [PDF]

open access: yes, 2012
In contrast to the neutrophilic inflammation found in the airway lumen, lymphocytes predominate in the airway wall of Cystic fibrosis (CF) patients.
Tan, Hui-leng
core   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Change of Th17 lymphocytes and Treg/Th17 in Typical and Atypical Optic Neuritis (.pdf)

open access: yes, 2016
Typical and atypical optic neuritis (ON) are two types of autoimmune inflammatory diseases of the optic nerve that causes acute vision loss, and which are difficult to distinguish in their early stages.
Xiaojun Zhang; Hengri Cong; Hanqiu Jiang; Jingting Peng; Shilei Cui; Lijuan Liu
core  

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