Results 231 to 240 of about 709,386 (365)
Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch+1 more
wiley +1 more source
The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li+10 more
wiley +1 more source
The insufficient sensitivity of single circulating tumor DNA (ctDNA)‐molecular residual disease (MRD) prediction remains unresolved and hinders the clinical implementation of ctDNA. Through prospective cohort study, independent validations, and mechanism exploration from peripheral blood and tumor tissue, we demonstrate that ctDNA‐based STK11/KEAP1 ...
Yu Wang+10 more
wiley +1 more source
EXPRESSION OF TH17-LYMPHOCYTE ADAPTER – TRAF3IP2 IN THE SKIN OF PSORIASIS PATIENTS
В. Р. Хайрутдинов+5 more
openalex +2 more sources
Mo1728 Regulation of Intestinal Cholinergic TH17 Lymphocytes by the Sympathetic Nervous System
Shobhit Dhawan+3 more
openalex +1 more source
Deciphering Novel Communication Patterns in T Regulatory Cells From Very Old Adults
Graphical summary depicting the changes in the co‐receptor landscape (a), migratory potential (b), differentiation program (c) and communication networks (d) in Tregs from the ‐< 66‐year‐old cohort versus the 85‐year‐olds. ABSTRACT Regulatory T cells (Tregs) are important in maintaining tolerance and are key players in immunity.
Tegan McTaggart+11 more
wiley +1 more source
Abbreviations: BLOC1S1, biogenesis of lysosome organelles complex 1 subunit 1; cGAS, cyclic GMP‐AMP synthase; GATA3, GATA binding protein 3; IgE, immunoglobulin E; IKK, inhibitor of nuclear factor kappa‐B kinase; IL, interleukin; mtDNA, mitochondrial DNA; NF‐κB, nuclear factor‐kappa B; OVA, ovalbumin; MC903, vitamin D3 analog; STING, stimulator of ...
Rahul Sharma+8 more
wiley +1 more source