Combined TLR2/TLR4 activation equip non-mucosal dendritic cells to prime Th1 cells with gut tropism. [PDF]
Zúquete S +11 more
europepmc +1 more source
Increased Th1 Cells with Disease Resolution of Active Pulmonary Tuberculosis in Non-Atopic Patients. [PDF]
Lo CY +6 more
europepmc +1 more source
Stable and Functional Regulatory T Cells for Adoptive Cell Therapy
Deprivation of CD28 signaling combined with CDK8/19 inhibition induces stable iTregs with demethylation of Treg‐DRs. Re‐stimulation of these iTregs with additional agents further enhances their suppressive function. The generated S/F‐iTregs suppress inflammation in vivo, and subset of the suppressed Tconvs is converted into de novo pTregs, contributing
Norihisa Mikami
wiley +1 more source
Lymphocytic Esophagitis With Predominance of CD4 T Cells and Expansion of Th1 Cells Is Associated With Achalasia. [PDF]
Muller K +6 more
europepmc +1 more source
Seismic analysis and design of tunnels within fault ground: A review
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang +6 more
wiley +1 more source
hsa_circ_0007755 competitively adsorbs miR-27b-3p to mediate CXCL2 expression and recruit Th1 cells to promote hypertrophic scars development. [PDF]
Qi J, Wu Y, Liu Y, Ma J, Wang Z.
europepmc +1 more source
In vivo CRISPR screens reveal a HIF-1α-mTOR-network regulates T follicular helper versus Th1 cells. [PDF]
Huang B +15 more
europepmc +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Rapamycin Modulates the Polarisation of CD4+ T Cells Towards T<sub>H</sub>1 Cells in Patients with Active Granulomatosis with Polyangiitis and Microscopic Polyangiitis. [PDF]
Ha JW, Yoon T, Kwon OC, Park YB, Lee SW.
europepmc +1 more source

