Results 171 to 180 of about 8,035 (194)
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Decreased circulating Th22 and Th17 cells in patients with aplastic anemia
Clinica Chimica Acta, 2015Aplastic anemia (AA) is an immune-mediated disorder and mainly related to active destruction of hematopoietic cells by effector T lymphocytes. T helper (Th) 22 cells characterized as a novel subset of CD4+ T cells participate in the pathogenesis of autoimmune and hematological diseases.
Ting Lu +6 more
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Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis
Journal of Clinical Immunology, 2011T-helper (Th) 22 and Th17 cells are implicated in the pathogenesis of autoimmune diseases. The roles of Th22 cells in the pathophysiology of rheumatoid arthritis (RA) remain unsettled.CD4(+)IFNγ(-)IL17(-)IL-22(+) T cells (Th22 cells), CD4(+)IFNγ(-)IL-22(-)IL17(+) T cells (pure Th17 cells), CD4(+)IL17(+) T cells (Th17 cells), and CD4(+)IFNγ(+) T cells ...
Lei, Zhang +12 more
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Intrarenal and Urinary Th9 and Th22 Cytokine Gene Expression in Lupus Nephritis
The Journal of Rheumatology, 2015Objective.We studied the urinary sediment mRNA level of Th9- and Th22-related cytokines in patients with systemic lupus erythematosus (SLE).Methods.We quantified urinary mRNA levels of interleukin (IL) 9, IL-10, IL-22, and their corresponding transcription factors in 73 patients with active lupus nephritis, 13 patients with hypertensive nephrosclerosis
Cathy Choi-Wan, Luk +8 more
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Th22 cells in autoimmunity: a review of current knowledge.
European annals of allergy and clinical immunology, 2015Newly identified T helper cell 22 (Th22) is a subset of CD4+ T cells with specific properties apart from other known CD4+ T cell subsets. Th22 is obviously discrete from Th17 and Th1 subsets by production of interleukin (IL)-22 but not IL-17 or IFN-γ, and also with distinguished expression of aryl hydrocarbon receptor (AHR) as the key transcription ...
G, Azizi, R, Yazdani, A, Mirshafiey
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The role of IL-22 and Th22 cells in human skin diseases
Journal of Dermatological Science, 2013Interleukin (IL)-22 is a cytokine that is involved in the modulation of tissue responses during inflammation. It is produced by immune cell subsets such as T cells, while the expression of its receptor is restricted to cells of non-hematopoietic origin, particularly epithelial cells.
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Pathogenic Th17 and Th22 cells are increased in patients with autoimmune thyroid disorders
Endocrine, 2017To study the levels of pathogenic and non-pathogenic Th17 and Th22 cells in autoimmune thyroid disorders patients. Although Th17 cells seem to play an important role in the pathogenesis of thyroid autoimmune disorders, the specific subsets of these lymphocytes have not been analyzed in this condition.We assessed the levels of Th17 (pathogenic and non ...
Marlen, Vitales-Noyola +6 more
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[Change and significance of Th22 cells in patients with aplastic anemia].
Zhonghua yi xue za zhi, 2014To explore the proportion of Th22 cells in peripheral blood of patients with aplastic anemia (AA) and evaluate its significance.From January 2011 to June 2012, a total of 47 AA patients were recruited and divided into 4 groups: severe aplastic anemia (SAA) pre-therapy (group A, n = 11), non-severe aplastic anemia (NSAA) pre-therapy (group B, n = 12 ...
Li-min, Liu +7 more
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Th22/IL-22 mediates the progression of HBV-related hepatocellular carcinoma via STAT3
Cytotechnology, 2022Mingwen Huang, Yong Huang
exaly
Th22 and related cytokines in inflammatory and autoimmune diseases.
Expert Opinion on Therapeutic Targets, 2013Daoxin Ma
exaly