Results 101 to 110 of about 4,589,213 (294)

The role of the chitinase-like protein BRP-39 in allergic asthma [PDF]

, 2009
Diese Studien zeigen, dass das Chitinase-ähnliche Protein BRP-39 eine entscheidende Rolle in der Pathogenese einer Th2 Entzündung in der Lunge spielt.
Koller, Barbara
core   +1 more source

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

PLoS Pathogens, 2015
Pulmonary mycoses are often associated with type-2 helper T (Th2) cell responses. However, mechanisms of Th2 cell accumulation are multifactorial and incompletely known.
Darin L Wiesner, Charles A Specht, Chrono K Lee, Kyle D Smith, Liliane Mukaremera, S Thera Lee, Chun G Lee, Jack A Elias, Judith N Nielsen, David R Boulware, Paul R Bohjanen, Marc K Jenkins, Stuart M Levitz, Kirsten Nielsen   +13 more
doaj   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Prevention of arthritis by interleukin 10-producing B cells [PDF]

, 2003
In this study we have shown that activation of arthritogenic splenocytes with antigen and agonistic anti-CD40 gives raise to a B cell population that produce high levels of interleukin (IL)-10 and low levels of interferon (IFN)-{gamma}. Transfer of these
Mauri, C., Mushtaq, N., Marco Londei, Claudia Mauri, Naseem Mushtaq, Gray, D., Londei, M., David Gray   +7 more
core   +1 more source

Delayed Activation Kinetics of Th2- and Th17 Cells Compared to Th1 Cells

Cells, 2017
During immune responses, different classes of T cells arise: Th1, Th2, and Th17. Mobilizing the right class plays a critical role in successful host defense and therefore defining the ratios of Th1/Th2/Th17 cells within the antigen-specific T cell ...
Andrea Duechting, Anna Przybyla, Stefanie Kuerten, Paul V. Lehmann   +3 more
doaj   +1 more source

Th1 and Th2 cells in autoimmunity [PDF]

Clinical and Experimental Immunology, 1995
P, Druet, R, Sheela, L, Pelletier
openaire   +3 more sources

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype [PDF]

, 2002
Background"Alternatively-activated" macrophages are found in Th2-mediated inflammatory settings such as nematode infection and allergic pulmonary inflammation.
Nair, Meera G, P'ng Loke, John Parkinson, Parkinson, John, Judith E Allen, Loke, P'ng, Blaxter, Mark, Meera G Nair, Guiliano, David, Mark Blaxter, Allen, Judith E, David Guiliano   +11 more
core   +1 more source

ILC2s Induce Adaptive Th2-Type Immunity in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Mediators of Inflammation, 2019
To investigate the effect of ILC2s on Th2-type adaptive immunity during the acute exacerbation of chronic obstructive pulmonary disease (AECOPD), the study enrolled healthy people, stable COPD patients, and AECOPD patients.
Min Jiang, Huifang Liu, Zheng Li, Jing Wang, Fengbo Zhang, Kaixiu Cao, Fengsen Li, Jianbing Ding   +7 more
doaj   +1 more source

Th2 cell

Citation: 'Th2 cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13719 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source