Results 1 to 10 of about 170,058 (167)

Targeting CXCR1/2 suppresses TH2/TH17 cell responses and inhibits dual-pathology allergic lung inflammation [PDF]

open access: yesJournal of Allergy and Clinical Immunology: Global
Background: Many chronic inflammatory diseases are driven by TH2 and TH17 immune responses and represent a major public health burden. While monoclonal antibodies against individual TH2 or TH17 cytokines or receptors show clinical benefit, their efficacy
Koa Hosoki, MD, PhD   +3 more
doaj   +2 more sources

Crosstalk between ILC2s and Th2 cells varies among mouse models

open access: yesCell Reports, 2023
Summary: Type 2 T helper (Th2) cells and group 2 innate lymphoid cells (ILC2s) provide protection against helminth infection and are involved in allergic responses. However, their relative importance and crosstalk during type 2 immune responses are still
Jangsuk Oh   +2 more
exaly   +3 more sources

Evaluation of IFN-γ and T-bet Expression Levels as Possible Molecular Markers of Schizophrenia [PDF]

open access: yesJournal of Cell and Molecular Research, 2020
Schizophrenia is an irritating mental disorder that affects around 1% of the world's population. The immune system contributes to the onset of the disease, particularly through production and secretion of some cytokines.
Roghaye Lorestani   +3 more
doaj   +1 more source

T helper cell subsets and related target cells in acute COVID-19

open access: yesИнфекция и иммунитет, 2022
Current review presents a brief overview of the immune system dysregulation during acute COVID-19 and illustrates the main alterations in peripheral blood CD4+ T-cell (Th) subsets as well as related target cells.
I. V. Kudryavtsev   +2 more
doaj   +1 more source

A Case of Pruritic Urticarial Papules and Plaques of Pregnancy: Pathophysiology and Serum Cytokine Profile

open access: yesCase Reports in Dermatology, 2021
We report a case of pruritic urticarial papules and plaques of pregnancy (PUPPP) starting with target lesions on both forearms at the end of second pregnancy.
Mai Ishikawa-Nishimura   +4 more
doaj   +1 more source

Th1/Th2 Imbalance and Elevated PD-L1 in Pleural Effusion Predict the Risk of Multi-Drug Resistant Tuberculous Pleuritis [PDF]

open access: yesIranian Journal of Immunology, 2020
Background: Patient immune status might be indicative of the variance in bacterial genetics in drug-resistant tuberculous pleuritis and could be used for predicting the risk of multi-drug resistant tuberculous pleuritis (MDR-TB).
Hongyan Xu   +3 more
doaj   +1 more source

Th1, Th2, and Th17 cytokines in systemic lupus erythematosus

open access: yesAutoimmunity, 2020
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the breakdown of immune tolerance leading to excessive inflammation and tissue damage.
Farhana Muhammad Yusoff   +2 more
doaj   +1 more source

Helminthiasis, eosinophils, COVID-19 and vaccination

open access: yesSouthern African Journal of Infectious Diseases, 2022
No abstract available.
Miles B. Markus
doaj   +1 more source

Review – Helicobacter: inflammation, immunity and vaccines [PDF]

open access: yesMicrobiota in Health and Disease, 2021
Helicobacter pylori is a bacterium that colonizes the human stomach and is the risk factor for severe gastroduodenal diseases, such as gastric cancer, gastric lymphoma, autoimmune gastritis and peptic ulcer. H.
M. D’Elios, M. de Bernard
doaj   +1 more source

The attenuation effect of low piperine Piper nigrum extract on doxorubicin-induced toxicity of blood chemical and immunological properties in mammary tumour rats

open access: yesPharmaceutical Biology, 2022
Context Many natural extracts have been shown to minimize the toxicity of doxorubicin (Dox). Low piperine Piper nigrum L. (Piperaceae) extract (PFPE) is a natural extract containing many types of antioxidants that may reduce Dox toxicities.
Jirakrit Saetang   +7 more
doaj   +1 more source

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