Beyond CCR7: dendritic cell migration in type 2 inflammation
Conventional dendritic cells (cDCs) are crucial antigen-presenting cells that initiate and regulate T cell responses, thereby shaping immunity against pathogens, innocuous antigens, tumors, and self-antigens. The migration of cDCs from peripheral tissues
Audrey Meloun +2 more
doaj +1 more source
Serum Levels of Seven General Cytokines in Acute Brucellosis Before and After Treatment
Yunxia Tang,1,2,* Chenjie Ma,1,2,* Huali Sun,3 Siyuan Yang,1,2 Fengting Yu,1,2 Xingwang Li,1,2 Linghang Wang1,2 1Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Clinical Center for HIV/AIDS, Capital ...
Tang Y +6 more
doaj
Suppression of allergic airway inflammation by helminth-induced regulatory T cells [PDF]
Allergic diseases mediated by T helper type (Th) 2 cell immune responses are rising dramatically in most developed countries. Exaggerated Th2 cell reactivity could result, for example, from diminished exposure to Th1 cell–inducing microbial infections ...
Lamb, Jonathan +11 more
core +1 more source
Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]
Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid +15 more
core +1 more source
The Concept of Pathogenic TH2 Cells: Collegium Internationale Allergologicum Update 2021. [PDF]
T helper (TH) cells have evolved into distinct subsets that mediate specific immune responses to protect the host against a myriad of infectious and noninfectious challenges.
Bertschi, Nicole L. +2 more
core +1 more source
The Role of Food Allergy in Eosinophilic Esophagitis
Jeffrey M Wilson, Rung-chi Li, Emily C McGowan Division of Allergy and Immunology, University of Virginia, Charlottesville, VA, USACorrespondence: Jeffrey M WilsonDivision of Allergy & Clinical Immunology, University of Virginia, Charlottesville, VA ...
Wilson JM, Li R, McGowan EC
doaj
Role of IL-25 in Immunity [PDF]
IL-25 a 2o KDa protein mostly known as IL-17E, encoded by chromosome 14, and containing 117 amino acids. Cytokine IL-17 family consists of 6 members; IL-17A to IL-17F, among which IL-25 has a unique structure and function. The receptor of IL-25 (IL-17BR)
Azar Valizadeh +3 more
doaj +1 more source
A Sting in the Tale of Th2 Immunity [PDF]
Allergies are widely considered misguided Th2 cell responses. In this issue, Palm et al. (2013) and Marichal et al. (2013) show that mice mount anti-venom Th2 cell responses that share components of the "allergic" response but confer protection.
Gutierrez, Dario A. +1 more
openaire +2 more sources
TH2 cytokines from malignant cells suppress TH1 responses and enforce a global TH2 bias in leukemic cutaneous T-cell lymphoma [PDF]
PURPOSE: In leukemic cutaneous T-cell lymphoma (L-CTCL), malignant T cells accumulate in the blood and give rise to widespread skin inflammation. Patients have intense pruritus, increased immunoglobulin E (IgE), and decreased T-helper (TH)-1 responses ...
Kupper, Thomas S. +19 more
core +2 more sources
Doxycycline for the treatment of breast cancer-related lymphedema
Purpose: Secondary lymphedema is a common complication of cancer treatment for which no effective drug treatments yet exist. Level I clinical data suggests that doxycycline is effective for treating filariasis-induced lymphedema, in which it decreases ...
Stav Brown +5 more
doaj +1 more source

