Innate immune system and preeclampsia
Frontiers in Immunology, 2014 Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda +3 more
doaj +1 more source
Lymphocyte subsets and the role of Th1/Th2 balance in stressed chronic pain patients [PDF]
, 2007 Background: The complex regional pain syndrome (CRPS) and fibromyalgia (FM) are chronic pain syndromes occurring in highly stressed individuals. Despite the known connection between the nervous system and immune cells, information on distribution of ...
Beyer, Antje +7 more
core +1 more source
Journal of Inflammation Research, 2022 Anish Maskey,1 Kamal Srivastava,1,2 Gary Soffer,3 David Dunkin,4 Qian Yuan,5 Xiu-Min Li1,6 1Department of Pathology, Microbiology & Immunology, New York Medical College, Valhalla, NY, USA; 2General Nutraceutical Technology, LLC, Elmsford, NY, USA ...
Maskey A +5 more
doaj
CD4 T-cell subsets in Malaria: TH1/TH2 revisited
Frontiers in Immunology, 2015 CD4+ T cells have been shown to play a central role in immune control of infection with Plasmodium parasites. At the erythrocytic stage of infection, IFN-γ production by CD4+ T cells and CD4+ T-cell help for the B-cell response are required for control ...
Damian ePerez-Mazliah, Jean eLanghorne
doaj +1 more source
CD11a polymorphisms regulate TH2 cell homing and TH2-related disease [PDF]
Journal of Allergy and Clinical Immunology, 2014 TH2-dependent diseases vary in severity according to genotype, but relevant gene polymorphisms remain largely unknown. The integrin CD11a is a critical determinant of allergic responses, and allelic variants of this gene might influence allergic phenotypes.We sought to determine major CD11a allelic variants in mice and human subjects and their ...
Knight, John +6 more
openaire +4 more sources
Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]
, 2007 Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S +9 more
core +2 more sources
Frontiers in Immunology, 2013 We have demonstrated that cardiac fibrosis arises from the differentiation of monocyte-derived fibroblasts. We present here evidence that this process requires sequential Th1 and Th2 induction promoting analogous M1 (classically activated) and M2 ...
JoAnn eTrial +5 more
doaj +1 more source
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. [PDF]
The Journal of Immunology, 2007 Abstract IL-27 up-regulates Th1 but down-regulates Th2 responses. However, its molecular mechanism and regulatory effects on polarized Th2 cells remain unclear. In this study, we have revealed that IL-27 inhibits Th2 cell development as well as Th2 cytokines production from already polarized Th2 cells by down-regulation of GATA-3 and ...
Tomohiro, Yoshimoto +4 more
openaire +3 more sources
The relative involvement of Th1 and Th2 associated immune responses in the expulsion of a primary infection of Heligmosomoides polygyrus in mice of differing response phenotype. [PDF]
, 2003 T helper cell (Th1 and Th2) associated responses were examined following a primary infection with the gastrointestinal nematode Heligmosomoides polygyrus in five inbred strains of mice with different resistance phenotypes.
Lammas, David +7 more
core +1 more source
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype [PDF]
, 2013 We previously demonstrated inhibition of ovalbumin (OVA)-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae.
Al-Riyami, Lamyaa +8 more
core +4 more sources