Results 21 to 30 of about 170,157 (266)
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. [PDF]
The Journal of Immunology, 2007 Abstract IL-27 up-regulates Th1 but down-regulates Th2 responses. However, its molecular mechanism and regulatory effects on polarized Th2 cells remain unclear. In this study, we have revealed that IL-27 inhibits Th2 cell development as well as Th2 cytokines production from already polarized Th2 cells by down-regulation of GATA-3 and ...
Tomohiro, Yoshimoto +4 more
openaire +3 more sources
Frontiers in Immunology, 2013 We have demonstrated that cardiac fibrosis arises from the differentiation of monocyte-derived fibroblasts. We present here evidence that this process requires sequential Th1 and Th2 induction promoting analogous M1 (classically activated) and M2 ...
JoAnn eTrial +5 more
doaj +1 more source
Beyond CCR7: dendritic cell migration in type 2 inflammation
Frontiers in ImmunologyConventional dendritic cells (cDCs) are crucial antigen-presenting cells that initiate and regulate T cell responses, thereby shaping immunity against pathogens, innocuous antigens, tumors, and self-antigens. The migration of cDCs from peripheral tissues
Audrey Meloun +2 more
doaj +1 more source
Serum Levels of Seven General Cytokines in Acute Brucellosis Before and After Treatment
Infection and Drug Resistance, 2021 Yunxia Tang,1,2,* Chenjie Ma,1,2,* Huali Sun,3 Siyuan Yang,1,2 Fengting Yu,1,2 Xingwang Li,1,2 Linghang Wang1,2 1Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Clinical Center for HIV/AIDS, Capital ...
Tang Y +6 more
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The Role of Food Allergy in Eosinophilic Esophagitis
Journal of Asthma and Allergy, 2020 Jeffrey M Wilson, Rung-chi Li, Emily C McGowan Division of Allergy and Immunology, University of Virginia, Charlottesville, VA, USACorrespondence: Jeffrey M WilsonDivision of Allergy & Clinical Immunology, University of Virginia, Charlottesville, VA ...
Wilson JM, Li R, McGowan EC
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Role of IL-25 in Immunity [PDF]
Journal of Clinical and Diagnostic Research, 2015 IL-25 a 2o KDa protein mostly known as IL-17E, encoded by chromosome 14, and containing 117 amino acids. Cytokine IL-17 family consists of 6 members; IL-17A to IL-17F, among which IL-25 has a unique structure and function. The receptor of IL-25 (IL-17BR)
Azar Valizadeh +3 more
doaj +1 more source
A Sting in the Tale of Th2 Immunity [PDF]
Immunity, 2013 Allergies are widely considered misguided Th2 cell responses. In this issue, Palm et al. (2013) and Marichal et al. (2013) show that mice mount anti-venom Th2 cell responses that share components of the "allergic" response but confer protection.
Gutierrez, Dario A. +1 more
openaire +2 more sources
Doxycycline for the treatment of breast cancer-related lymphedema
Frontiers in Pharmacology, 2022 Purpose: Secondary lymphedema is a common complication of cancer treatment for which no effective drug treatments yet exist. Level I clinical data suggests that doxycycline is effective for treating filariasis-induced lymphedema, in which it decreases ...
Stav Brown +5 more
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Th2 Cytokines and Atopic Dermatitis [PDF]
Journal of Clinical & Cellular Immunology, 2011 Atopic dermatitis (AD), a chronic relapsing inflammatory skin disease, is increasing in prevalence around the world. Intensive research is ongoing to understand the mechanisms involved in the development of AD and offer new treatment options for patients suffering from AD.
Eric B, Brandt, Umasundari, Sivaprasad
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Th1/Th2 differentiation and B cell function by the atypical PKCs and their regulators
Frontiers in Immunology, 2012 The members of the atypical PKCs (aPKC) kinase subfamily, PKCζ and PKCλ/ι, as well as their adapters, p62 and Par-6, form part of the PB1-domain-containing group of signaling regulators.
Pilar eMartin, Jorge eMoscat
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