Results 41 to 50 of about 170,157 (266)

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

open access: yesAdvanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan   +6 more
wiley   +1 more source

ANALYSIS OF T HELPER SUBPOPULATIONS (Th1, Th2, Treg, Th17, ACTIVATED T-HELPERS) BY MEANS OF FLOW CYTOMETRY

open access: yesМедицинская иммунология, 2014
. Over last years, huge efforts are made in order to improve analytic techniques for T lymphocyte subpopulations. Appropriate studies on T-helper cells are also subject to extensive research.
S. V. Khaidukov, A. V. Zurochka
doaj   +1 more source

Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity. [PDF]

open access: yesPLoS ONE, 2013
Functionally polarized CD4+ T helper (Th) cells such as Th1, Th2 and Th17 cells are central to the regulation of acquired immunity. However, the molecular mechanisms governing the maintenance of the polarized functions of Th cells remain unclear.
Tetsuya Sasaki   +9 more
doaj   +1 more source

A Hybrid Computational Framework for PCF‐based SPR Sensor With Machine Learning and xAI

open access: yesAdvanced Materials Interfaces, EarlyView.
A photonic crystal fiber‐based surface plasmon resonance (SPR) sensor integrating rectangular air holes along with conventional circular air holes achieves exceptional wavelength sensitivity of 15,000 nm/RIU across a broad refractive index range of 1.31–1.39. Integrated machine learning with explainable AI (xAI) models achieves high prediction accuracy
Mahabur Rahman Fahim   +3 more
wiley   +1 more source

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

open access: yesAdvanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo   +4 more
wiley   +1 more source

Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice

open access: yesAsian Pacific Journal of Tropical Biomedicine
Objective: To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum, and a purified antigen. Methods: Mice were subjected to the following treatments: (1) Purified recombinant K39 (
Araújo Lucelina S.   +8 more
doaj   +1 more source

Passive Directional Water Transport on Superhydrophobic Gradient Textures Fabricated by Direct Laser Interference Patterning

open access: yesAdvanced Materials Technologies, EarlyView.
Microstructures fabricated by two‐beam DLIP combining spatial‐period and roughness gradients are fabricated to enhance directional transport of water droplets. The coupled gradients increase transport distance by 160% and strongly suppress motion against the gradient, demonstrating an effective strategy for controlled droplet manipulation.
Tianhao Wu   +3 more
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu   +15 more
wiley   +1 more source

Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling.

open access: yesPLoS ONE, 2021
Histamine, which is mainly produced by mast cells and basophils, participates in various allergic symptoms, and some studies have reported that macrophages also produce histamine.
Naruhito Iwasaki   +6 more
doaj   +1 more source

Mercury: god of Th2 cells? [PDF]

open access: yesClinical and Experimental Immunology, 1995
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openaire   +2 more sources

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