Th2 Cytokines and Atopic Dermatitis [PDF]
Journal of Clinical & Cellular Immunology, 2011 Atopic dermatitis (AD), a chronic relapsing inflammatory skin disease, is increasing in prevalence around the world. Intensive research is ongoing to understand the mechanisms involved in the development of AD and offer new treatment options for patients suffering from AD.
Eric B, Brandt, Umasundari, Sivaprasad
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Th1/Th2 differentiation and B cell function by the atypical PKCs and their regulators
Frontiers in Immunology, 2012 The members of the atypical PKCs (aPKC) kinase subfamily, PKCζ and PKCλ/ι, as well as their adapters, p62 and Par-6, form part of the PB1-domain-containing group of signaling regulators.
Pilar eMartin, Jorge eMoscat
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A Case of Papuloerythroderma Successfully Treated with Dupilumab
Case Reports in Dermatology, 2022 Papuloerythroderma is an erythroderma characterized by the composition of dense paving stone shape papules and intertriginous uninvolved skin on the abdominal wall and is often intractable and accompanied by itching.
Ayaka Mizuno +4 more
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The role of the chitinase-like protein BRP-39 in allergic asthma [PDF]
, 2009 Diese Studien zeigen, dass das Chitinase-ähnliche Protein BRP-39 eine entscheidende Rolle in der Pathogenese einer Th2 Entzündung in der Lunge spielt.
Koller, Barbara
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Prostaglandin D_2 Augments Low-dose Antigen-induced Th2 Type Airway Inflammation in Mice [PDF]
, 2003 Prostaglandin D_2 (PGD_2), a mast cell-derived lipid mediator is detected in lage amounts in airways of asthmatics, but its role of largely unkown. To clarify the role of PGD_2 in Th2-type airway inflammation which characterizes asthma, we studied the ...
Eda, Fukiko +5 more
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International Journal of COPD, 2023 Gang Chen,1 Qing Mu,1 Zhao-Ji Meng2 1Department of Respiratory and Critical Care Medicine, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 2Department of Immune Allergy, Henan ...
Chen G, Mu Q, Meng ZJ
doaj
Contribution of basophils to cutaneous immune reactions and Th2-mediated allergic responses
Frontiers in Immunology, 2015 Basophils are potent effector cells of innate immunity and also play a role in T helper 2 (Th2)-mediated allergic responses. But, although their in vitro functions are well studied, their in vivo functions remain largely unknown.
Atsushi eOtsuka, Kenji eKabashima
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Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]
, 2008 Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
White, Janice +11 more
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PATHOGENETIC ROLE OF CYTOKINES IN CHILDHOOD ROTAVIRUS INFECTION
Медицинская иммунология, 2014 . Results of cytokine network studies system in children with rotavirus infection are presented. Concentrations of cytokines were determined at both local and systemic levels.
S. N. Benyova +2 more
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Chitinase and Fizz family members are a generalized feature of nematode infection with selective Upregulation of Ym1 and F10.1 by antigen-presenting cells [PDF]
, 2005 Ym1 and Fizz1 are secreted proteins that have been identified in a variety of Th2-mediated inflammatory settings. We originally found Ym1 and Fizz1 as highly expressed macrophage genes in a Brugia malayi infection model.
Coulson, P.S. +23 more
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