Results 61 to 70 of about 216,273 (211)

Anatomy of a Discovery: M1 and M2 Macrophages

Frontiers in Immunology, 2015
M1 and M2 macrophage-type responses kill or repair in vivo. The unique ability of macrophages to make these polar opposite type of responses provides primary host protection and maintains tissue homeostasis throughout the animal kingdom.
Charles Dudley Mills
doaj   +1 more source

Th2-associated immunity to bacteria in teenagers and susceptibility to asthma

, 2010
Th2-associated immunity to bacteria in teenagers and susceptibility to ...
EM Hollams (14457882), BJ Hales (14457861), W Huvenne (13373007), PG Holt (14457411), BJ Holt (14457651), C Bachert (7727126), M Serralha (13307868), WR Thomas (14457876), PD Sly (14453628), F Parsons (13369173), S Ahlstedt (13371417), NH De Klerk (14457849)   +11 more
core  

IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype [PDF]

, 2002
Background"Alternatively-activated" macrophages are found in Th2-mediated inflammatory settings such as nematode infection and allergic pulmonary inflammation.
Nair, Meera G, P'ng Loke, John Parkinson, Parkinson, John, Judith E Allen, Loke, P'ng, Blaxter, Mark, Meera G Nair, Guiliano, David, Mark Blaxter, Allen, Judith E, David Guiliano   +11 more
core   +1 more source

Effects of chronic ascariasis and trichuriasis on cytokine production and gene expression in human blood: a cross-sectional study. [PDF]

, 2011
BACKGROUND: Chronic soil-transmitted helminth (STH) infections are associated with effects on systemic immune responses that could be caused by alterations in immune homeostasis.
Cooper, Philip J, Broncano, N, Reina Ortiz, Miguel, Miguel Reina Ortiz, Schreiber Fernanda, David J Lewis, Alexander Neal, Lewis, David J, Chico, ME, Benitez Susana, David J. Lewis, Vaca Maritza, Nely Broncano, Chico, Martha E, Dougan Gordon, Reina Ortiz, M, Fernanda Schreiber, Martha E. Chico, Schreiber, F, Alexander, N, Lewis, DJ, Philip J. Cooper, Gordon Dougan, Cooper Philip J., Dougan, Gordon, Neal Alexander, Vaca, Maritza, Benitez, S, Vaca, M, Martha E Chico, Benitez, Susana, Philip J Cooper, Broncano Nely, Alexander, Neal, Maritza Vaca, Susana Benitez, Dougan, G, Lewis David J., Schreiber, Fernanda, Cooper, PJ, Reina Ortiz Miguel, Cooper, Philip, Broncano, Nely, Chico Martha E.   +43 more
core   +1 more source

Dissecting the enigma of scleroderma: possible involvement of the kynurenine pathway

Pteridines, 2017
The kynurenine pathway (KP) is the metabolic pathway via which L-tryptophan is converted to nicotinamide. It serves important immune-regulatory roles. This article will review the evidence for involvement of the KP in scleroderma and present a possible ...
Noakes Rowland
doaj   +1 more source

Polarizing T and B cell responses by APC-targeted subunit vaccines.

Frontiers in Immunology, 2015
Current influenza vaccines mostly aim at the induction of specific neutralizing antibodies. While antibodies are important for protection against a particular virus strain, T cells can recognize epitopes that will offer broader protection against ...
Gunnveig eGrødeland, Even eFossum, Bjarne eBogen, Bjarne eBogen   +3 more
doaj   +1 more source

TH2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood

, 1997
TH2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early ...
A Yabuhara (13369773), C Macaubas (13368867), SL Prescott (14458611), PG Holt (14457411), BJ Holt (14457651), TJ Venaille (14461206), W Habre (13366293), PD Sly (14453628)   +7 more
core  

Rôle de la mutation Vav1R63W dans la sensibilité à l’asthme allergique [PDF]

, 2012
Dans mon équipe d’accueil, une dissection génétique à l'aide des lignées de rats congéniques BN.LEW a permis d'identifier un polymorphisme sur le gène Vav1.
Bayol, Camille
core  

EPILT_RNA-seq-Th2-Th2-Th1-WT-KO-Dec15_WT

, 2019
<p>Adapter type : Illumina - Insert : 300pb for Sample RNAseq-Th2-WT386, 500pb for Sample RNAseq-Th2-Th1-WT459, 300pb for Sample RNAseq-Th2-WT399, 500pb for Sample RNAseq-Th2-Th1-WT495, 500pb for Sample RNAseq-Th2-Th1-KO481, 500pb for Sample RNAseq-
Adoue Veronique
core   +1 more source

TRIM28 mediates Mettl5 ubiquitination to promotes Th2 polarization

Frontiers in Immunology
BackgroundTh2 polarization is the primary characteristic of airway allergy (AA) and many other immune disorders. Further elucidation of its mechanism is necessary.
Beiping Miao, Lihua Mo, Lihua Mo, Shihan Miao, Xiwen Zhang, Haoyue Zheng, Yixuan Dong, Bailing Xie, Yuanyi Zhang, Yun Liao, Yun Liao, Yu Liu, Ping Tang, Pingchang Yang   +13 more
doaj   +1 more source