Results 81 to 90 of about 216,273 (211)

Chimeric Antigen-LgDNA Nanoparticles Attenuate Airway Th2 Polarization [PDF]

Ruien Chen,1,* Huamei Zou,1,* Xiuwen Ye,1,* Bailing Xie,2 Aizhi Zhang,3 Lihua Mo,4 Yu Liu,4 Huanping Zhang,5 Gui Yang,1 Pingchang Yang2 1Department of Otolaryngology, Longgang Central Hospital affiliated to Guangzhou University of Chinese ...
Zou H, Liu Y, Yang G, Zhang H, Yang P, Mo L, Chen R, Ye X, Zhang A, Xie B   +9 more
core  

A Real-World Study of Tofacitinib in Indian Patients with Refractory Moderate-to-Severe Atopic Dermatitis, its Economic Considerations and Immunological Rationale

Indian Dermatology Online Journal
Background: The response of atopic dermatitis (AD) to different biologics and JAK inhibitors (JAKibs) is variable due to the varied immunological endotypes of AD.
Kabir Sardana, Savitha Sharath, Sumitra Kumari Meena, Ananta Khurana, Bhawuk Dhir   +4 more
doaj   +1 more source

The Primary Responses of Murine Neonatal Lymph Node CD4+ Cells are Th2-skewed and are Sufficient for the Development of Th2-biased Memory

Clinical and Developmental Immunology, 2003
Exposure of neonatal mice to antigen often results in Th2-biased responses in later life. Examples of this Th2 tendency are (a) secondary antibody responses dominated by the Th2-associated IgG1 isotype and (b) Th2-mediated tolerance to alloantigens.
Becky Adkins, Yurong Bu, Vladimir Vincek, Patricia Guevara   +3 more
doaj   +1 more source

Th2 Cytokines Inhibit Lymphangiogenesis

PLOS ONE, 2015
Lymphangiogenesis is the process by which new lymphatic vessels grow in response to pathologic stimuli such as wound healing, inflammation, and tumor metastasis. It is well-recognized that growth factors and cytokines regulate lymphangiogenesis by promoting or inhibiting lymphatic endothelial cell (LEC) proliferation, migration and differentiation. Our
Ira L Savetsky, Swapna Ghanta, Jason C Gardenier, Jeremy S Torrisi, Gabriela D García Nores, Geoffrey E Hespe, Matthew D Nitti, Raghu P Kataru, Babak J Mehrara   +8 more
openaire   +4 more sources

Perioperative immune responses in cancer patients undergoing digestive surgeries

World Journal of Surgical Oncology, 2009
Background Th1/Th2 cell balance is thought to be shifted toward a Th2-type immune response not only by malignancy but also by surgical stress. The aim of this study was to estimate perioperative immune responses with respect to the Th1/Th2 balance in ...
Miyauchi Takayuki, Hanaki Norikazu, Nishioka Masanori, Ishikawa Masashi, Kashiwagi Yutaka, Ioki Hiromi, Kagawa Akihiro, Nakamura Yoichi   +7 more
doaj   +1 more source

Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk. [PDF]

, 2015
BACKGROUND: Prostaglandin D2 (PGD2) and cysteinyl leukotrienes (cysLTs) are lipid mediators derived from mast cells, which activate TH2 cells. The combination of PGD2 and cysLTs (notably cysteinyl leukotriene E4 [LTE4]) enhances TH2 cytokine production ...
Paul Klenerman, Panse, Isabel, Roy Pettipher, Pettipher, Roy, Vinall, Shân L., Klenerman, Paul, Shân L. Vinall, Hunter, Michael G., Isabel Panse, Klenerman, P, Jackson, DG, Hunter, MG, Fergusson, J, Ahmed N. Hegazy, Jackson, David, Vinall, SL, Fergusson, Joannah, Jackson, David G., Maryam Salimi, Xue, Luzheng, Graham Ogg, Ussher, JE, Ogg, G, Salimi, M, Salimi, Maryam, Panse, I, Ussher, James E., David G. Jackson, Xue, L, Joannah Fergusson, Hegazy, Ahmed N., Pettipher, R, Luzheng Xue, James E. Ussher, Hegazy, AN, Ogg, Graham, Michael G. Hunter   +36 more
core   +1 more source

Identifizierung und Charakterisierung muriner und humaner Th2/1-Hybridzellen in Th2-gesteuerten Erkrankungen

, 2019
CD4+ T cells differentiate into diverse cell lineages with distinct effector functions, based on their produced signature cytokines. Previous studies have reported that T helper (Th) cell subsets can adopt characteristics of two opposing T cell ...
Bock, Cristin Nadine
core   +1 more source

The role of CD4+T cells in host protective responses against cutaneous Leishmaniasis using genome-wide transcriptomics. [PDF]

, 2013
Includes abstract.Includes bibliographical references.Leishmania major is a protozoan parasite and infection in the human host causes severe cutaneous Leishmaniasis.
Smith, Liezel C
core   +1 more source

Th2-associated local reactions to the acellular diphtheria-tetanus- pertussis vaccine in 4- to 6-year-old children

, 2005
Acellular vaccines against diphtheria-tetanus-pertussis (acellular pertussis) (DTaP) are being progressively introduced into vaccination programs worldwide, with the aim of reducing T-helper 1 (Th1)-associated reactogenicity associated with the cellular ...
D Suriyaarachchi (13369170), L Feddema (13371384), PG Holt (14457411), PD Sly (14453628), ST Yerkovich (14458884), E Fisher (7693061), J Rowe (9877307), P Richmond (13371381), R Loh (13369182)   +8 more
core  

ChIP-Th2-Dec15_WT

, 2019
<p>Adapter type : Illumina - Insert : 350pb for Sample Th2-WT-H3K9ac-Dec15, 350pb for Sample Th2-WT-H3K9me3-Dec15, 350pb for Sample Th2-Setdb1-H3K9ac-Dec15, 350pb for Sample Th2-Setdb1-H3K9me3-Dec15, 350pb for Sample Th2-Suv39h1-H3K9ac-Dec15, 350pb
Adoue Veronique
core   +1 more source