Results 11 to 20 of about 170,157 (266)
A SLAT in the Th2 Signalosome [PDF]
There is abundant information on the distinguishing features of TCR-mediated signaling in Th1 and Th2 cells. However, the primary signals that determine the commitment and differentiation of naive T cells toward those T helper subsets, especially prior to the contribution of polarizing cytokines, remain elusive.
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Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
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Pollinosis in children and adolescents: modern aspects of pathogenesis and tendencies in therapy
The development of pollinosis in children and adolescents is determined by the influence of genetic and environmental factors. The pathogenetic basis of pollinosis in children and adolescents is the differentiation of Th0 to Th2, activation of Th2cells ...
I. I. Balabolkin
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Hypericum perforatum Alleviates Ovalbumin-Induced Asthma through Downregulating TH2 and Upregulating TH1 Related Parameters in BALB/C Mice [PDF]
Background: Allergic asthma is a chronic and inflammatory disease of the respiratory tract, which is characterized by inflammation, airway obstruction and swelling. Anti-inflammatory compounds can be used to improve the disease severity.
Fahimeh Rostamabadi +3 more
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The prevalence of iron (Fe) deficiency and subclinical lead (Pb) toxicity is high in developing countries like India, and information on their potential additive effects on immune responses is scant.
Srinivasa Reddy Yathapu +4 more
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Th1/Th2 in aspergillosis [PDF]
The outcome of the Th1/Th2 balance is a critical determinant of the outcome in invasive aspergillosis. The innate immune system encounters the pathogen first. Dendritic cells (DC) appear to be the critical fulcrum at the intersection of the innate immune system, and which receptors are engaged, particularly which Toll-like receptors are triggered by ...
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Innate immune system and preeclampsia
Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda +3 more
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CD11a polymorphisms regulate TH2 cell homing and TH2-related disease [PDF]
TH2-dependent diseases vary in severity according to genotype, but relevant gene polymorphisms remain largely unknown. The integrin CD11a is a critical determinant of allergic responses, and allelic variants of this gene might influence allergic phenotypes.We sought to determine major CD11a allelic variants in mice and human subjects and their ...
Knight, John +6 more
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Anish Maskey,1 Kamal Srivastava,1,2 Gary Soffer,3 David Dunkin,4 Qian Yuan,5 Xiu-Min Li1,6 1Department of Pathology, Microbiology & Immunology, New York Medical College, Valhalla, NY, USA; 2General Nutraceutical Technology, LLC, Elmsford, NY, USA ...
Maskey A +5 more
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CD4 T-cell subsets in Malaria: TH1/TH2 revisited
CD4+ T cells have been shown to play a central role in immune control of infection with Plasmodium parasites. At the erythrocytic stage of infection, IFN-γ production by CD4+ T cells and CD4+ T-cell help for the B-cell response are required for control ...
Damian ePerez-Mazliah, Jean eLanghorne
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