Results 11 to 20 of about 216,273 (211)

CD4CD25 Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection [PDF]

, 2011
Eggs of the helminth Schistosoma mansoni accumulate in the colon following infection and generate Th2-biassed inflammatory granulomas which become down- modulated in size as the infection proceeds to chronicity.
Adrian P. Mountford, Aynsley, Sarah A, Sarah A. Aynsley, Cook, Peter C, Hogg, Karen G., Karen G. Hogg, Peter C. Cook, Mark C. Coles, Cook, Peter C; id_orcid, Peter C Cook, Cook Peter C., Cook, Peter C., Aynsley, Sarah A., Mountford Adrian P., Joseph D. Turner, Gavin R Jenkins, Aynsley Sarah A., Mountford, Adrian P, Paveley, Ross A., Ross A Paveley, Ross A. Paveley, Coles, Mark C, Turner, Joseph, Karen G Hogg, Hogg Karen G., Jenkins, Gavin R., Adrian P Mountford, Turner, Joseph D, Sarah A Aynsley, Paveley Ross A., Coles Mark C., Gavin R. Jenkins, Paveley, Ross A, Jenkins, Gavin R, Mark C Coles, Coles, Mark C., Hogg, Karen G, Joseph D Turner, Jenkins Gavin R., Mountford, Adrian P., Turner Joseph D.   +40 more
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A differential interplay between the expression of Th1/Th2/Treg related cytokine genes in Teladorsagia circumcincta infected DRB1*1101 carrier lambs [PDF]

, 2011
peer-reviewedSubstantial debate exists on whether the immune response between sheep resistant and susceptible to gastrointestinal nematodes can be differentiated into a Th1 and Th2 phenotype.
Barbara Good, Good Barbara, Good, Barbara, Mulcahy, Grace, Sweeney, Torres, Mulcahy Grace, Hassan, Musa, Hanrahan, James P, Sweeney Torres, Grace Mulcahy, Musa Hassan, Hanrahan James P, James P Hanrahan, Hassan Musa, Hanrahan, James P., Torres Sweeney   +15 more
core   +1 more source

Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung

European Medical Journal Respiratory, 2020
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
doaj   +1 more source

In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines [PDF]

, 2002
We show that a combination of the immunosuppressive drugs, vitamin D3 and Dexamethasone, induced human and mouse naive CD4(+) T cells to differentiate in vitro into regulatory T cells.
Hawrylowicz, C.M., Robert L. Coffman, André Boonstra, Richards, David F, Richards, D.F., Catherine M. Hawrylowicz, Savelkoul, H.F.J., Savelkoul, HFJ (Huub), Crain, Chad, Anne O'Garra, O' Garra, A, de Waal-Malefyt, R., Coffman, R.L., O'Garra, Anne, Cua, D.J., Chad Crain, Cua, DJ, Huub F. Savelkoul, Coffman, RL, Waal-Malefyt, R., de, Cua, Daniel J, Savelkoul, Huub F, Barrat, Franck J, de Waal-Malefyt, René, de Waal-Malefyt, R, Hawrylowicz, Catherine M; id_orcid, Crain, C., Barrat, FJ, Barrat, F.J., Crain, C, Coffman, Robert L, Boonstra, P.A., Daniel J. Cua, Hawrylowicz, CM, Franck J. Barrat, David F. Richards, O'Garra, A., René de Waal-Malefyt, Richards, DF, Boonstra, Andre   +39 more
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Pollinosis in children and adolescents: modern aspects of pathogenesis and tendencies in therapy

Аллергология и Иммунология в Педиатрии, 2023
The development of pollinosis in children and adolescents is determined by the influence of genetic and environmental factors. The pathogenetic basis of pollinosis in children and adolescents is the differentiation of Th0 to Th2, activation of Th2cells ...
I. I. Balabolkin
doaj   +1 more source

Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis [PDF]

, 2014
T helper 2 (Th2) cells regulate helminth infections, allergic disorders, tumor immunity, and pregnancy by secreting various cytokines. It is likely that there are undiscovered Th2 signaling molecules.
Xiuwei Zhang, Sarah A. Teichmann, Zhang, Xiuwei, Dingler, Felix A., Felix A. Dingler, Teichmann, Sarah A., Valentina Proserpio, Berthold Göttgens, Dingler, Felix A, Kolodziejczyk, Aleksandra A, Teichmann, Sarah A, Proserpio, V, Taylor, Angela E., Hebenstreit, Daniel, Taylor, Angela E; id_orcid, Proserpio, Valentina, Haim-Vilmovsky, Liora, McKenzie, Andrew N J, Liora Haim-Vilmovsky, Göttgens, Berthold, Andrew N.J. McKenzie, Arlt, Wiebke, Angela E. Taylor, McKenzie, Andrew N.J., Daniel Hebenstreit, Kolodziejczyk, Aleksandra A., Aleksandra A. Kolodziejczyk, Wiebke Arlt, Victoria Moignard, Moignard, Victoria, McKenzie, Andrew N. J., Bidesh Mahata, Mahata, Bidesh   +32 more
core   +1 more source

Hypericum perforatum Alleviates Ovalbumin-Induced Asthma through Downregulating TH2 and Upregulating TH1 Related Parameters in BALB/C Mice [PDF]

Pharmaceutical Sciences
Background: Allergic asthma is a chronic and inflammatory disease of the respiratory tract, which is characterized by inflammation, airway obstruction and swelling. Anti-inflammatory compounds can be used to improve the disease severity.
Fahimeh Rostamabadi, Reza Nosratabadi, Amir Rahnama, Vahid Mohammadi-Shahrokhi   +3 more
doaj   +1 more source

Effect of lead exposure and nutritional iron-deficiency on immune response: A vaccine challenge study in rats

Journal of Immunotoxicology, 2020
The prevalence of iron (Fe) deficiency and subclinical lead (Pb) toxicity is high in developing countries like India, and information on their potential additive effects on immune responses is scant.
Srinivasa Reddy Yathapu, Narendra Babu Kondapalli, Sarath Babu Srivalliputturu, Rajkumar Hemalatha, Dinesh Kumar Bharatraj   +4 more
doaj   +1 more source

A SLAT in the Th2 Signalosome [PDF]

Immunity, 2003
There is abundant information on the distinguishing features of TCR-mediated signaling in Th1 and Th2 cells. However, the primary signals that determine the commitment and differentiation of naive T cells toward those T helper subsets, especially prior to the contribution of polarizing cytokines, remain elusive.
openaire   +3 more sources

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]

, 2014
IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M., Katherine A. Smith, Maizels, Rick M, Rick M. Maizels, Smith, Katherine A., Smith, Katherine A   +5 more
core   +1 more source