Aberrant expressions of circulating lncRNA NEAT1 and microRNA-125a are linked with Th2 cells and symptom severity in pediatric allergic rhinitis. [PDF]
Wu X +6 more
europepmc +1 more source
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza +6 more
wiley +1 more source
Metabolic adaptations of ILC2 and Th2 cells in type 2 immunity. [PDF]
Kania AK +3 more
europepmc +1 more source
We have developed a technology enabling high‐resolution organic light‐emitting diode displays exceeding 1000 ppi with crystal indium oxide backplane. Introducing a partition wall between sub‐pixels and employing our novel OCTILE pixel arrangement allow application of a fine metal mask process to high‐resolution displays.
Shingo Eguchi +11 more
wiley +1 more source
Single-cell and chromatin accessibility profiling reveals regulatory programs of pathogenic Th2 cells in allergic asthma. [PDF]
Khan M +11 more
europepmc +1 more source
New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender +2 more
wiley +1 more source
Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s. [PDF]
Nomura A +9 more
europepmc +1 more source
JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni +6 more
wiley +1 more source
The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review. [PDF]
Teodoro TH +5 more
europepmc +1 more source
Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab
ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle +7 more
wiley +1 more source

