Results 161 to 170 of about 267,317 (298)

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Holistic bone developing microenvironment engineered apoptotic extracellular vesicles recapitulate multidimensional developmental signatures in adult and senile bone repair

Interdisciplinary Medicine, EarlyView.
The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu, Jieyun Xu, Yuan Zhao, Xinyu Guo, Hongcheng Chen, Junlong Xue, Yong Ao, Linjun Zhang, Xiaomeng Gao, Xueli Mao, Songtao Shi, Zetao Chen   +11 more
wiley   +1 more source

IL-33 promotes transcriptional and metabolic adaptations of tissue-resident Th2 cells. [PDF]

J Immunol
Kania AK, Sanin DE, Gu X, Gidley M, Kokosinski E, Smith A, Pearce E, Pearce EJ.   +7 more
europepmc   +1 more source

Elevated Neddylation Pathway Promotes Th2 Cells Infiltration by Transactivating STAT5A in Hepatocellular Carcinoma. [PDF]

Front Oncol, 2021
Zhou L, Zhang L, Chen S, Sun D, Qu J.
europepmc   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre, Pedro H. F. Silva, Marina C. G. Del‐Arco, Raquel F. Gerlach, Rene S. Oliezer, José E. Tanus‐Santos, Luciene C. Figueiredo, Janaina S. A. M. Evangelista, Flávia A. C. Furlaneto, Michel R. Messora, Sérgio Luiz Salvador   +10 more
wiley   +1 more source

L-Phenylalanine is a metabolic checkpoint of human Th2 cells. [PDF]

Cell Rep Med
Kulkarni AJ, Rodriguez-Coira J, Stocker N, Radzikowska U, García-Cívico AJ, Delgado Dolset MI, Contreras N, Jardón Parages I, Saiz Sanchez V, Serrano P, Izquierdo E, Gomez-Casado C, Sanchez-Solares J, Pablo-Torres C, Obeso D, Moreno-Aguilar C, Espinazo ML, Eljaszewicz A, Koch J, Baerenfaller K, Heider A, Tan G, Zhakparov D, Escribese MM, Ruiz-Leon B, Akdis CA, Argüello RJ, Barber D, Villaseñor A, Sokolowska M.   +29 more
europepmc   +1 more source

BDNF Acts as a Prognostic Factor Associated with Tumor-Infiltrating Th2 Cells in Pancreatic Adenocarcinoma. [PDF]

Dis Markers, 2021
Zhu Y, Zhang C, Zhao D, Li W, Zhao Z, Yao S, Zhao D.   +6 more
europepmc   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Th1 and Th2 cells in equine endometrosis and their interactions with endometrial fibroblasts. [PDF]

Sci Rep
Wójtowicz A, Sadowska A, Molcan T, Słyszewska M, Drzewiecka EM, Tobolski D, Ferreira-Dias G, Szóstek-Mioduchowska A.   +7 more
europepmc   +1 more source

Allergen recognition by specific effector Th2 cells enables IL-2-dependent activation of regulatory T-cell responses in humans. [PDF]

Allergy, 2023
Lozano-Ojalvo D, Tyler SR, Aranda CJ, Wang J, Sicherer S, Sampson HA, Wood RA, Burks AW, Jones SM, Leung DYM, de Lafaille MC, Berin MC.   +11 more
europepmc   +1 more source