Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro +7 more
wiley +1 more source
CXCR6 recruits Th2 cells and promotes liver fibrosis in schistosomiasis japonica. [PDF]
Zhang Y +7 more
europepmc +1 more source
Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population
Abstract We present a case series of seven pediatric patients with collagenous gastritis (CG) with the aim of contributing data to existing literature about this rare disease to assist in the understanding and management of these patients. Gross nodularity seen on esophagogastroduodenoscopy and increased subepithelial collagen on biopsy were noted in ...
Megan Emiliani +2 more
wiley +1 more source
PGI2 signaling metabolically reprograms CD4 Th2 cells and represses allergic airway inflammation. [PDF]
Zhou W +10 more
europepmc +1 more source
Immune Metabolism of IL-4-Activated B Cells and Th2 Cells in the Context of Allergic Diseases. [PDF]
Lin YJ, Goretzki A, Schülke S.
europepmc +1 more source
Abstract Crohn's disease (CD) and eosinophilic gastrointestinal diseases (EGIDs) are distinct inflammatory entities, but eosinophilic disease may emerge as a paradoxical immune complication of anti–tumor necrosis factor therapy. We report a 12‐year‐old boy with terminal ileal CD who developed severe eosinophilic gastritis and ileitis, peripheral ...
Jonathan Dudzik +3 more
wiley +1 more source
Tissue-Resident Th2 Cells in Type 2 Immunity and Allergic Diseases. [PDF]
Mannion JM, Rahimi RA.
europepmc +1 more source
Gata3 ZsG and Gata3 ZsG-fl: Novel murine Gata3 reporter alleles for identifying and studying Th2 cells and ILC2s in vivo. [PDF]
Gurram RK +10 more
europepmc +1 more source
Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley +1 more source
Corrigendum to "Lung-resident memory Th2 cells regulate pulmonary cryptococcosis by inducing type-II granuloma formation" [Mucosal Immunol. 18(3) (2025) 631-642]. [PDF]
Ueno K +4 more
europepmc +1 more source

