Results 131 to 140 of about 62,396 (288)

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano, Carolina Gorodetsky, Darcia Paul, Jürgen Germann, Aaron Loh, Han Yan, Peter L. Carlen, Sara Breitbart, Andres M. Lozano, George M. Ibrahim, Suneil K. Kalia   +10 more
wiley   +1 more source

Trajectory of hippocampal fibres to the contralateral anterior thalamus and mammillary bodies in rats, mice, and macaque monkeys

Brain and Neuroscience Advances, 2019
The routes by which the hippocampal formation projects bilaterally to the anterior thalamic nuclei and mammillary bodies were examined in the mouse, rat, and macaque monkey.
Mathias L. Mathiasen, Rebecca C. Louch, Andrew D. Nelson, Christopher M. Dillingham, John P. Aggleton   +4 more
doaj   +1 more source

Cognitive Outcome After Deep Brain Stimulation for Refractory Obsessive–Compulsive Disorder: A Systematic Review

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis, Annelien Duits, Mégan M. G. H. van de Veerdonk, Anne E. P. Mulders, Koen R. J. Schruers, Yasin Temel, Linda Ackermans, Albert F. G. Leentjens   +7 more
wiley   +1 more source

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo, Nagore Hernández‐Pinedo, Josefa Zaldivar‐Diez, Isabel Pérez‐Santos, José A. Obeso, Carmen Cavada, Javier Blesa   +6 more
wiley   +1 more source

Functional representation of vision within the mind: A visual consciousness model based in 3D default space [PDF]

, 2015
The human eyes and brain, which have finite boundaries, create a ‘‘virtual’’ space within our central nervous system that interprets and perceives a space that appears boundless and infinite.
Barnes, Vernon A., Crawford, Molly W., Ravinder, Jerath   +2 more
core  

Patient‐Reported Feedback Suggests an Alternative Sweet Spot for Deep Brain Stimulation Programming in Essential Tremor

Movement Disorders, EarlyView.
(1) To sample subjective patient rating using the Visual Analogue Scale (VAS), random stimulation parameters were presented to the study subjects. (2) Next, corresponding volumes of tissue activated (VTA) were generated and paired with VAS values.
Sophia Peschke, Jing Dong, Angelina Kirschner, Johannes Off, Juhi Shaik, Carla Palleis, Jan Hinnerk Mehrkens, Elisabeth Kaufmann, Maximilian Scherer, Thomas Koeglsperger   +9 more
wiley   +1 more source

Temporal Dynamics of Parkinson's Disease Tremor: Clinical and Neuroimaging Insights

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder clinically defined by three cardinal motor symptoms: bradykinesia, rigidity, and tremor. Although the natural history of bradykinesia and rigidity is well described, the evolution of tremor as the disease progresses remains controversial. Objectives The goal was to
Melanie Suette, Robert Matic, Marisa Koini, Lukas Gattermeyer‐Kell, Daniela Kern, Petra Katschnig‐Winter, Mariella Koegl, Maximilian Sackl, Christian Tinauer, Birgit Helmlinger, Manuel Leitner, Stefan Ropele, Daniela Pinter, Christian Enzinger, Stephan Seiler, Petra Schwingenschuh   +15 more
wiley   +1 more source

Putamen Atrophy as a Predictive Factor of Efficacy of GPi‐DBS in Dystonia‐Dyskinesia Syndrome Secondary to Perinatal Anoxic Encephalopathy

Movement Disorders, EarlyView.
Abstract Background Perinatal hypoxic–ischemic encephalopathy (HIE) is a severe condition resulting from impaired oxygen delivery to the developing brain, often leading to both motor deficits and dystonia‐dyskinetic syndromes (DDS). In selected cases, deep brain stimulation of the globus pallidus internus (GPi‐DBS) may provide a therapeutic option ...
Marylou Grasso, Pierre‐Olivier Moser, Sidonie Sauvageot, Valérie Gil, Emilie Chan‐Seng, Emily Sanrey, Philippe Coubes, Gaëtan Poulen   +7 more
wiley   +1 more source

Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation

Movement Disorders, EarlyView.
Abstract Adaptive deep brain stimulation (aDBS) represents an important evolution in the treatment of Parkinson's disease (PD), building on conventional DBS (cDBS) by adjusting stimulation in response to real‐time physiological signals. By enabling dynamic targeting of disease‐related neural activity, aDBS offers the potential for more precise ...
Thomas Koeglsperger, Maximilian Scherer, Andrea A. Kühn, Alexandre Eusebio, Alfonso Fasano, Joachim K. Krauss   +5 more
wiley   +1 more source

Temporal Interference Stimulation Modulates Resting State Functional Connectivity of Motor Circuit in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Transcranial temporal interference stimulation (TIs) targeting the subthalamic nucleus (STN) is a novel noninvasive neuromodulation approach with potential to improve motor symptoms in Parkinson's disease (PD). However, its underlying neuroimaging mechanisms remain unclear.
Yongxin Xu, Chenhao Yang, Yichao Du, Xiaonan Shen, Tingting Li, Yufeng Zhang, Zijun Lu, Jie Zhuang, Nan Chen, Yulian Zhu, Chencheng Zhang, Jiaojiao Lü, Lingyan Huang, Lu Li, Jianqiang Lü, Zhenyu Qian, Zhen Wang, Jian Zhang, Junhong Zhou, Yu Liu   +19 more
wiley   +1 more source