Results 111 to 120 of about 62,396 (288)
Introduction Although widespread cortical asymmetries have been identified in Alzheimer's disease (AD), thalamic asymmetries and their relevance to clinical severity in AD remain unclear.
Audrey Low +13 more
doaj +1 more source
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Epilepsy surgery: From bench to the clinics
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley +1 more source
Neonatal seizures and GABAergic drugs: Scylla and Charybdis?
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson +2 more
wiley +1 more source
Background Attention deficit hyperactivity disorder (ADHD) is frequently accompanied by both internalizing and externalizing symptoms, yet the neuroanatomical underpinnings of these comorbidities remain unclear, particularly within thalamic subnuclei ...
Yongheng Zhao +10 more
doaj +1 more source
Aims: Sleep dysfunction is common in the prodromal stages of Alzheimer’s disease. Several thalamic nuclei are implicated in promoting and maintaining sleep.
Sita Shah +4 more
doaj +1 more source
Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren +12 more
wiley +1 more source
We report the case of a woman presenting with changes on cerebral imaging a year and a half after a bi-thalamic (predominantly left-sided) infarction including lateral and medial thalamic nuclei.
Eloi eMagnin +4 more
doaj +1 more source
Postmortem MRI reveals distinct structural features in sudden unexpected death in epilepsy
Abstract Magnetic resonance imaging (MRI) abnormalities have been reported in individuals who later die from sudden unexpected death in epilepsy (SUDEP), but their specificity and predictive value remain uncertain. Postmortem MRI (PM‐MRI) offers a unique opportunity to distinguish structural features associated with SUDEP from changes related to ...
Andrea Hill +9 more
wiley +1 more source
Resting state functional thalamic connectivity abnormalities in patients with post-stroke sleep apnoea: a pilot case-control study [PDF]
OBJECTIVE: Sleep apnoea is common after stroke, and has adverse effects on the clinical outcome of affected cases. Its pathophysiological mechanisms are only partially known.
CALISTRI, VALENTINA +9 more
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