Results 81 to 90 of about 62,396 (288)

The genetic architecture of the human thalamus and its overlap with ten common brain disorders

Nature Communications, 2021
Differences in thalamic structure have been observed in several psychiatric disorders, but the genetic overlap has not been explored. Here, the authors perform a genome-wide association study on thalamic nuclei volume and find genetic loci in common ...
Torbjørn Elvsåshagen, Alexey Shadrin, Oleksandr Frei, Dennis van der Meer, Shahram Bahrami, Vinod Jangir Kumar, Olav Smeland, Lars T. Westlye, Ole A. Andreassen, Tobias Kaufmann   +9 more
doaj   +1 more source

Moving beyond neurophobia to cultivate the neuroquisitive learner

Anatomical Sciences Education, EarlyView.
Abstract “Neurophobia,” a pervasive fear of the neurological sciences, poses a significant barrier in medical education, affecting learners and physicians worldwide. Its consequences are far‐reaching, contributing to a limited neurology workforce and diminished confidence among non‐specialists in managing neurological conditions.
Joanna R. Appel, Kirsten A. Porter‐Stransky   +1 more
wiley   +1 more source

Thalamo-cortical network activity between migraine attacks. Insights from MRI-based microstructural and functional resting-state network correlation analysis [PDF]

, 2016
BACKGROUND: Resting state magnetic resonance imaging allows studying functionally interconnected brain networks. Here we were aimed to verify functional connectivity between brain networks at rest and its relationship with thalamic microstructure in ...
Colonnese, Claudio, Coppola, Gianluca, DI LORENZO, Cherubino, Di Lorenzo, Giorgio, DI RENZO, Antonio, Lepre, Chiara, Parisi, Vincenzo, Pierelli, Francesco, Scapeccia, Marco, Schoenen, Jean, Serrao, Mariano, Tinelli, Emanuele   +11 more
core   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Subregional thalamic atrophy in Progressive Supranuclear Palsy: A machine learning study

NeuroImage: Clinical
Background: Several MRI studies have documented thalamic atrophy in Progressive Supranuclear Palsy (PSP), but investigations to date have considered the whole thalami, without evaluating their subcomponents. This study aimed to assess atrophy of thalamic
Camilla Calomino, Maria Giovanna Bianco, Chiara Camastra, Jolanda Buonocore, Pier Paolo Arcuri, Aldo Quattrone, Andrea Quattrone   +6 more
doaj   +1 more source

Distinct thalamic functional connectivity and volume patterns across focal epilepsies in children: A multimodal neuroimaging study

Epilepsia, EarlyView.
Abstract Objective The thalamus is a key hub in seizure propagation, and its nuclei are emerging targets for neuromodulation. However, the contributions of individual nuclei to epileptic networks remain unclear, particularly in children, who are less studied than adults.
Xiyu Feng, Aswin Chari, Maria H. Eriksson, Freya Prentice, Xiaosong He, Hua Xie, Leigh Sepeta, M. Zubair Tahir, Jonathan D. Clayden, Martin M. Tisdall, Torsten Baldeweg, Rory J. Piper   +11 more
wiley   +1 more source

Thalamic Circuit Diversity: Modulation of the Driver/Modulator Framework

Frontiers in Neural Circuits, 2016
The idea that dorsal thalamic inputs can be divided into drivers, which provide the primary excitatory drive for the relay of information to cortex, and modulators, which alter the gain of signal transmission, has provided a valuable organizing principle
Martha E Bickford
doaj   +1 more source

Forebrain Origins of Glutamatergic Innervation to the Rat Paraventricular Nucleus of the Hypothalamus: Differential Inputs to the Anterior Versus Posterior Subregions [PDF]

, 2011
The hypothalamic paraventricular nucleus (PVN) regulates numerous homeostatic systems and functions largely under the influence of forebrain inputs. Glutamate is a major neurotransmitter in forebrain, and glutamate neurosignaling in the PVN is known to ...
Cullinan, William E, Herman, James P., Jones, Kenneth R., Ulrich-Lai, Yvonne M., Ziegler, Dana R.   +4 more
core   +3 more sources

Rhythms in longitudinal thalamic recordings are linked to seizure risk

Epilepsia, EarlyView.
Abstract Objective Seizure unpredictability remains a major clinical challenge for people with epilepsy. Previous works have shown that seizure risk is associated with circadian and multi‐day cycles in both brain and physiological signals. However, it remains unclear whether neural activity from deep brain structures such as the anterior nucleus of the
Xinbing Zhang, Zachary T. Sanger, Thomas Lisko, Steffen Ventz, Robert A. McGovern, Theoden I. Netoff   +5 more
wiley   +1 more source

The emotional gatekeeper: a computational model of attentional selection and suppression through the pathway from the amygdala to the inhibitory thalamic reticular nucleus [PDF]

, 2016
In a complex environment that contains both opportunities and threats, it is important for an organism to flexibly direct attention based on current events and prior plans. The amygdala, the hub of the brain's emotional system, is involved in forming and
Barbas, Helen, Bullock, Daniel, John, Yohan J., Zikopoulos, Basilis   +3 more
core   +2 more sources