Results 141 to 150 of about 55,234 (296)
Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]
, 2011 GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Crunelli, Vincenzo +2 more
core
The effect of neural adaptation of population coding accuracy
, 2011 Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear.
Cortes, J. M. +5 more
core +2 more sources
Geometric Analysis of Synchronization in Neuronal Networks with Global Inhibition and Coupling Delays [PDF]
, 2017 We study synaptically coupled neuronal networks to identify the role of coupling delays in network's synchronized behaviors. We consider a network of excitable, relaxation oscillator neurons where two distinct populations, one excitatory and one ...
Campbell, Sue Ann, Ryu, Hwayeon
core +2 more sources
Qihuang Needle Therapy for Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial
Movement Disorders, EarlyView.Abstract Background Motor symptoms in Parkinson's disease (PD) often respond incompletely to medication, highlighting the need for effective adjunctive therapies. Acupuncture may offer benefits, but high‐quality evidence for specialized techniques such as Qihuang needle therapy is lacking.
Wanqing Peng +11 more
wiley +1 more source
The Functional Role of Thalamocortical Coupling in the Human Motor Network
Journal of Neuroscience, 2019 The amplitude of high broadband activity in human cortical field potentials indicates local processing and has repeatedly been shown to reflect motor control in the primary motor cortex. In a group of male and female subjects affected by essential tremor
E. Opri +4 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade +7 more
wiley +1 more source
eLife, 2018 Highly distributed neural circuits are thought to support adaptive decision-making in volatile and complex environments. Notably, the functional interactions between prefrontal and reciprocally connected thalamic nuclei areas may be important when ...
Fabien Alcaraz +5 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu +9 more
wiley +1 more source
Cortical Sensory Responses Are Enhanced by the Higher-Order Thalamus
Cell Reports, 2016 In the mammalian brain, thalamic signals reach the cortex via two major routes: primary and higher-order thalamocortical pathways. While primary thalamocortical nuclei transmit sensory signals from the periphery, the function of higher-order ...
Rebecca A. Mease +2 more
doaj +1 more source
Thalamocortical network neuromodulation for epilepsy. [PDF]
Brain CommunObjectives Despite the growing interest in network-guided neuromodulation for epilepsy, uncertainty about the safety and long-term efficacy of thalamocortical stimulation persist. Our evaluation focused on the use of a 4-lead open-loop implantable pulse generator (IPG) for thalamocortical network neuromodulation.
Agashe S +12 more
europepmc +3 more sources